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Orla Maguire

Explore the profile of Orla Maguire including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 1155
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Recent Articles
1.
Alaklabi S, Maguire O, Pattnaik H, Zhang Y, Chow J, Wang J, et al.
Cancers (Basel) . 2024 Sep; 16(17). PMID: 39272962
The CLARINET trial led to the approval of lanreotide for the treatment of patients with gastroenteropancreatic neuroendocrine tumors (NETs). It is hypothesized that lanreotide regulates proliferation, hormone synthesis, and other...
2.
Seon B, Okazaki M, Duzen J, Matsuno F, Goey A, Maguire O
Leuk Res . 2024 Jan; 136():107436. PMID: 38232613
We identified unique molecular heterogeneity of CD79 of human B cell antigen receptor (BCR) that may open a new approach to the ongoing CD79b-targeted therapy of B cell tumors. The...
3.
Gandhi S, Opyrchal M, Grimm M, Slomba R, Kokolus K, Witkiewicz A, et al.
J Immunother Cancer . 2023 Nov; 11(11). PMID: 37963636
Background: Presence of cytotoxic T lymphocytes (CTL) in the tumor microenvironment (TME) predicts the effectiveness of cancer immunotherapies. The ability of toll-like receptor 3 (TLR3) ligands, interferons (IFNs) and COX2...
4.
Bertram-Ralph E, Maguire O, Columb M
Eur J Anaesthesiol . 2023 Aug; 40(9):622-623. PMID: 37530714
No abstract available.
5.
Elshoury A, Maguire O, Conway A, Tario J, Soh K, Ross M, et al.
Transplant Cell Ther . 2022 Nov; 29(2):112.e1-112.e9. PMID: 36436782
Hypoxic conditions preserve the multipotency and self-renewing capacity of murine bone marrow and human cord blood stem cells. Blood samples stored in sealed blood gas tubes become hypoxic as leukocytes...
6.
Rosenberg C, Bill M, Maguire O, Petersen M, Kjeldsen E, Hokland P, et al.
Cytometry B Clin Cytom . 2021 Oct; 102(2):107-114. PMID: 34648681
Background: Studies in T-cell acute lymphoblastic leukemia (T-ALL) have shown that leukemic blast populations may display immunophenotypic heterogeneity. In the clinical setting, evaluation of measurable residual disease during treatment and...
7.
Fountzilas C, Bajor D, Mukherjee S, Saltzman J, Witkiewicz A, Maguire O, et al.
Clin Cancer Res . 2021 Oct; 27(24):6726-6736. PMID: 34645646
Purpose: We evaluated the antitumor efficacy of cetuximab in combination with pembrolizumab in patients with wild-type (RASwt), metastatic colorectal adenocarcinoma (mCRC). Patients And Methods: In this phase Ib/II study, cetuximab...
8.
Sribenja S, Maguire O, Attwood K, Buas M, Palmer J, Ambrosone C, et al.
Am J Cancer Res . 2021 Jul; 11(6):3263-3270. PMID: 34249460
In humans, parity without breastfeeding increases risk of estrogen receptor-negative (ER-) breast cancer and is associated with hypermethylation of , a pioneer factor regulating lineage commitment of mammary gland luminal...
9.
Ngai L, Ma C, Maguire O, Do A, Robert A, Logan A, et al.
Eur J Haematol . 2021 May; 107(3):343-353. PMID: 34053123
Objectives: This study aims to retrospectively assess C-lectin-like molecule 1 (CLL-1) bimodal expression on CD34+ blasts in acute myeloid leukemia (AML) patients (total N = 306) and explore potential CLL-1...
10.
Utley A, Chavel C, Lightman S, Holling G, Cooper J, Peng P, et al.
Cell Rep . 2020 Jun; 31(12):107815. PMID: 32579940
Durable humoral immunity against epidemic infectious disease requires the survival of long-lived plasma cells (LLPCs). LLPC longevity is dependent on metabolic programs distinct from short-lived plasma cells (SLPCs); however, the...