Orion J Peterson
Overview
Explore the profile of Orion J Peterson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
99
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Srivastava N, Vomund A, Peterson O, Abousaway O, Li T, Kain L, et al.
bioRxiv
. 2024 Nov;
PMID: 39605669
Type 1 diabetes (T1D) affects a genetically susceptible population that develops autoreactive T cells attacking insulin-producing pancreatic β cells. Increasingly, neoantigens are recognized as critical drivers of this autoimmune response....
2.
Hu H, Vomund A, Peterson O, Srivastava N, Li T, Kain L, et al.
Nat Commun
. 2024 Sep;
15(1):8318.
PMID: 39333495
Autoimmune attack toward pancreatic β cells causes permanent loss of glucose homeostasis in type 1 diabetes (T1D). Insulin secretory granules store and secrete insulin but are also thought to be...
3.
Srivastava N, Hu H, Peterson O, Vomund A, Stremska M, Zaman M, et al.
Immunity
. 2024 May;
57(7):1629-1647.e8.
PMID: 38754432
The pancreatic islet microenvironment is highly oxidative, rendering β cells vulnerable to autoinflammatory insults. Here, we examined the role of islet resident macrophages in the autoimmune attack that initiates type...
4.
Wenzlau J, Peterson O, Vomund A, DiLisio J, Hohenstein A, Haskins K, et al.
Front Immunol
. 2024 Mar;
15:1348131.
PMID: 38455055
There is accumulating evidence that pathogenic T cells in T1D recognize epitopes formed by post-translational modifications of β-cell antigens, including hybrid insulin peptides (HIPs). The ligands for several CD4 T-cell...
5.
Srivastava N, Hu H, Vomund A, Peterson O, Baker R, Haskins K, et al.
Diabetes
. 2021 Sep;
70(12):2860-2870.
PMID: 34497137
Recognition of β-cell antigens by autoreactive T cells is a critical step in the initiation of autoimmune type1 diabetes. A complete protection from diabetes development in NOD mice harboring a...
6.
Vomund A, Lichti C, Peterson O, Arbelaez A, Wan X, Unanue E
J Exp Med
. 2021 Apr;
218(6).
PMID: 33822842
Assessing the self-peptides presented by susceptible major histocompatibility complex (MHC) molecules is crucial for evaluating the pathogenesis and therapeutics of tissue-specific autoimmune diseases. However, direct examination of such MHC-bound peptides...
7.
Hu H, Zakharov P, Peterson O, Unanue E
Proc Natl Acad Sci U S A
. 2020 Nov;
117(49):31319-31330.
PMID: 33229539
Autoimmune diabetes is one of the complications resulting from checkpoint blockade immunotherapy in cancer patients, yet the underlying mechanisms for such an adverse effect are not well understood. Leveraging the...
8.
Peterson O, Cornelison L, Durham P
J Med Food
. 2020 Apr;
23(12):1259-1265.
PMID: 32326809
Early life stress is a risk factor for development of migraine, a prevalent painful neurological disease characterized by sensitization and activation of trigeminal neurons. Secondary early life stress was previously...
9.
Wan X, Vomund A, Peterson O, Chervonsky A, Lichti C, Unanue E
Nat Immunol
. 2020 Apr;
21(5):589.
PMID: 32238948
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
10.
Wan X, Vomund A, Peterson O, Chervonsky A, Lichti C, Unanue E
Nat Immunol
. 2020 Mar;
21(4):455-463.
PMID: 32152506
The nature of autoantigens that trigger autoimmune diseases has been much discussed, but direct biochemical identification is lacking for most. Addressing this question demands unbiased examination of the self-peptides displayed...