Neetu Srivastava
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Explore the profile of Neetu Srivastava including associated specialties, affiliations and a list of published articles.
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22
Citations
207
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Recent Articles
1.
Srivastava N, Vomund A, Peterson O, Abousaway O, Li T, Kain L, et al.
bioRxiv
. 2024 Nov;
PMID: 39605669
Type 1 diabetes (T1D) affects a genetically susceptible population that develops autoreactive T cells attacking insulin-producing pancreatic β cells. Increasingly, neoantigens are recognized as critical drivers of this autoimmune response....
2.
Hu H, Vomund A, Peterson O, Srivastava N, Li T, Kain L, et al.
Nat Commun
. 2024 Sep;
15(1):8318.
PMID: 39333495
Autoimmune attack toward pancreatic β cells causes permanent loss of glucose homeostasis in type 1 diabetes (T1D). Insulin secretory granules store and secrete insulin but are also thought to be...
3.
Srivastava N, Hu H, Peterson O, Vomund A, Stremska M, Zaman M, et al.
Immunity
. 2024 May;
57(7):1629-1647.e8.
PMID: 38754432
The pancreatic islet microenvironment is highly oxidative, rendering β cells vulnerable to autoinflammatory insults. Here, we examined the role of islet resident macrophages in the autoimmune attack that initiates type...
4.
Chowdhury B, Das S, Bodhale N, Pandey S, Sudan R, Srivastava N, et al.
Cytokine
. 2023 Sep;
171:156373.
PMID: 37776719
Leishmania major and L. donovani cause cutaneous leishmaniasis and visceral leishmaniasis, respectively. Available chemotherapies suffer from toxicity, drug-resistance or high cost of production prompting the need for the discovery of...
5.
Fernandes S, Srivastava N, Pedicone C, Sudan R, Luke E, Dungan O, et al.
iScience
. 2023 Feb;
26(2):106071.
PMID: 36818285
Here we extend the understanding of how chemical inhibition of SHIP paralogs controls obesity. We compare different classes of SHIP inhibitors and find that selective inhibitors of SHIP1 or SHIP2...
6.
Sudan R, Fernandes S, Srivastava N, Pedicone C, Meyer S, Chisholm J, et al.
Front Immunol
. 2022 May;
13:830961.
PMID: 35603158
Humans homozygous for inactivating (lipopolysaccharide (LPS)-responsive beige-like anchor) mutations or with compound heterozygous mutations exhibit a spectrum of immune-related pathologies including inflammatory bowel disease (IBD). The cause of this pathology...
7.
Srivastava N, Hu H, Vomund A, Peterson O, Baker R, Haskins K, et al.
Diabetes
. 2021 Sep;
70(12):2860-2870.
PMID: 34497137
Recognition of β-cell antigens by autoreactive T cells is a critical step in the initiation of autoimmune type1 diabetes. A complete protection from diabetes development in NOD mice harboring a...
8.
Jha M, Sarode A, Bodhale N, Mukherjee D, Pandey S, Srivastava N, et al.
J Immunol
. 2020 Apr;
204(10):2734-2753.
PMID: 32245818
causes cutaneous leishmaniasis. An antileishmanial vaccine for humans is unavailable. In this study, we report development of two attenuated strains-5ASKH-HP and LV39-HP-by continuous culture (high passage) of the corresponding virulent...
9.
Fernandes S, Srivastava N, Sudan R, Middleton F, Shergill A, Ryan J, et al.
Front Immunol
. 2018 Jun;
9:1100.
PMID: 29872435
In our previous study, we observed a severe reduction in the Src homology 2-containing-inositol-phosphatase-1 (SHIP1) protein in a subpopulation of subjects from a small adult Crohn's Disease (CD) cohort. This...
10.
Park M, Sudan R, Srivastava N, Neelam S, Youngs C, Wang J, et al.
Sci Rep
. 2016 Nov;
6:36568.
PMID: 27824136
The PH-BEACH-WD40 (PBW) protein family members play a role in coordinating receptor signaling and intracellular vesicle trafficking. LPS-Responsive-Beige-like Anchor (LRBA) is a PBW protein whose immune function remains elusive. Here...