Onkar Sharma
Overview
Explore the profile of Onkar Sharma including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
387
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0
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Recent Articles
1.
Sharma S, Choudhary M, Sharma O, Injeti E, Mittal A
Comput Biol Chem
. 2024 Sep;
113:108185.
PMID: 39217892
Ficus viren has been traditionally used to treat diabetes, and its extract inhibits carbohydrate/lipid metabolism and possesses anti-hyperglycemic potential. However, there is conflicting investigation related to F. viren extract effect...
2.
Kaur N, Gupta P, Dutt V, Sharma O, Gupta S, Dua A, et al.
Arch Biochem Biophys
. 2024 Feb;
753:109922.
PMID: 38341069
Inflammation is the primary driver of skeletal muscle wasting, with oxidative stress serving as both a major consequence and a contributor to its deleterious effects. In this regard, regulation of...
3.
Cramer W, Sharma O, Zakharov S
Biochem J
. 2018 Dec;
475(23):3903-3915.
PMID: 30541793
Current problems in the understanding of colicin import across the outer membrane (OM), involving a range of cytotoxic mechanisms, are discussed: (I) Crystal structure analysis of colicin E3 (RNAase) with...
4.
Ladokhin A, Vargas-Uribe M, Rodnin M, Ghatak C, Sharma O
Toxins (Basel)
. 2017 Sep;
9(10).
PMID: 28937631
Cellular entry of diphtheria toxin is a multistage process involving receptor targeting, endocytosis, and translocation of the catalytic domain across the endosomal membrane into the cytosol. The latter is ensured...
5.
Hancz D, Westerlund E, Bastiat-Sempe B, Sharma O, Valfridsson C, Meyer L, et al.
mBio
. 2017 Jul;
8(4).
PMID: 28720729
Group A (GAS) is a common human pathogen and the etiologic agent of a large number of diseases ranging from mild, self-limiting infections to invasive life-threatening conditions. Two prominent virulence...
6.
Sharma O, OSeaghdha M, Velarde J, Wessels M
PLoS Pathog
. 2016 Mar;
12(3):e1005468.
PMID: 26938870
A global increase in invasive infections due to group A Streptococcus (S. pyogenes or GAS) has been observed since the 1980s, associated with emergence of a clonal group of strains...
7.
Sharma O, Collier R
Biochemistry
. 2014 Oct;
53(44):6934-40.
PMID: 25317832
The protective antigen (PA) moiety of anthrax toxin forms oligomeric pores in the endosomal membrane, which translocate the effector proteins of the toxin to the cytosol. Effector proteins bind to...
8.
Zakharov S, Sharma O, Zhalnina M, Yamashita E, Cramer W
Biochem Soc Trans
. 2012 Nov;
40(6):1463-8.
PMID: 23176499
Pathway I. Group A nuclease colicins parasitize and bind tightly (Kd ≤ 10(-9) M) to the vitamin B12 receptor on which they diffuse laterally in the OM (outer membrane) and...
9.
Rodnin M, Kyrychenko A, Kienker P, Sharma O, Vargas-Uribe M, Collier R, et al.
Biophys J
. 2011 Nov;
101(10):L41-3.
PMID: 22098755
The translocation (T) domain plays a key role in the action of diphtheria toxin and is responsible for transferring the N-terminus-attached catalytic domain across the endosomal membrane into the cytosol...
10.
Pentelute B, Sharma O, Collier R
Angew Chem Int Ed Engl
. 2011 Feb;
50(10):2294-6.
PMID: 21351339
No abstract available.