Kirill A Datsenko
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Explore the profile of Kirill A Datsenko including associated specialties, affiliations and a list of published articles.
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29
Citations
5880
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Recent Articles
1.
Shiriaeva A, Savitskaya E, Datsenko K, Vvedenskaya I, Fedorova I, Morozova N, et al.
Nat Commun
. 2019 Oct;
10(1):4603.
PMID: 31601800
Type I CRISPR-Cas loci provide prokaryotes with a nucleic-acid-based adaptive immunity against foreign DNA. Immunity involves adaptation, the integration of ~30-bp DNA fragments, termed prespacers, into the CRISPR array as...
2.
Musharova O, Sitnik V, Vlot M, Savitskaya E, Datsenko K, Krivoy A, et al.
Mol Microbiol
. 2019 Mar;
111(6):1558-1570.
PMID: 30875129
CRISPR interference occurs when a protospacer recognized by the CRISPR RNA is destroyed by Cas effectors. In Type I CRISPR-Cas systems, protospacer recognition can lead to «primed adaptation» - acquisition...
3.
Gall A, Hegarty A, Datsenko K, Westerman R, SanMiguel P, Csonka L
Mol Microbiol
. 2018 May;
109(3):327-344.
PMID: 29802740
We found that mutations that increased the transcription of the mgtCBR (Mg transport-related) operon conferred increased thermotolerance on this organism. The 5' leader of the mgtCBR mRNA contains two short...
4.
Musharova O, Klimuk E, Datsenko K, Metlitskaya A, Logacheva M, Semenova E, et al.
Nucleic Acids Res
. 2017 Feb;
45(6):3297-3307.
PMID: 28204574
During primed CRISPR adaptation spacers are preferentially selected from DNA recognized by CRISPR interference machinery, which in the case of Type I CRISPR-Cas systems consists of CRISPR RNA (crRNA) bound...
5.
Strotskaya A, Savitskaya E, Metlitskaya A, Morozova N, Datsenko K, Semenova E, et al.
Nucleic Acids Res
. 2017 Jan;
45(4):1946-1957.
PMID: 28130424
CRISPR-Cas systems provide prokaryotes with adaptive defense against bacteriophage infections. Given an enormous variety of strategies used by phages to overcome their hosts, one can expect that the efficiency of...
6.
Gall A, Datsenko K, Figueroa-Bossi N, Bossi L, Masuda I, Hou Y, et al.
Proc Natl Acad Sci U S A
. 2016 Nov;
113(52):15096-15101.
PMID: 27849575
In Salmonella enterica serovar Typhimurium, Mg limitation induces transcription of the mgtA Mg transport gene, but the mechanism involved is unclear. The 5' leader of the mgtA mRNA contains a...
7.
Kuznedelov K, Mekler V, Lemak S, Tokmina-Lukaszewska M, Datsenko K, Jain I, et al.
Nucleic Acids Res
. 2016 Oct;
44(22):10849-10861.
PMID: 27738137
The Escherichia coli type I-E CRISPR-Cas system Cascade effector is a multisubunit complex that binds CRISPR RNA (crRNA). Through its 32-nucleotide spacer sequence, Cascade-bound crRNA recognizes protospacers in foreign DNA,...
8.
Semenova E, Savitskaya E, Musharova O, Strotskaya A, Vorontsova D, Datsenko K, et al.
Proc Natl Acad Sci U S A
. 2016 Jun;
113(27):7626-31.
PMID: 27325762
Prokaryotic clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR associated (Cas) immunity relies on adaptive acquisition of spacers-short fragments of foreign DNA. For the type I-E CRISPR-Cas system from Escherichia coli,...
9.
Vorontsova D, Datsenko K, Medvedeva S, Bondy-Denomy J, Savitskaya E, Pougach K, et al.
Nucleic Acids Res
. 2015 Nov;
43(22):10848-60.
PMID: 26586803
CRISPR immunity depends on acquisition of fragments of foreign DNA into CRISPR arrays. For type I-E CRISPR-Cas systems two modes of spacer acquisition, naïve and primed adaptation, were described. Naïve...
10.
Boudry P, Semenova E, Monot M, Datsenko K, Lopatina A, Sekulovic O, et al.
mBio
. 2015 Oct;
6(5):e01508-15.
PMID: 26443462
No abstract available.