Ong Moua
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Explore the profile of Ong Moua including associated specialties, affiliations and a list of published articles.
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10
Citations
674
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Recent Articles
1.
Dwulet J, Ludin N, Piscopio R, Schleicher W, Moua O, Westacott M, et al.
Biophys J
. 2019 Nov;
117(11):2188-2203.
PMID: 31753287
Understanding how cell subpopulations in a tissue impact overall system function is challenging. There is extensive heterogeneity among insulin-secreting β-cells within islets of Langerhans, including their insulin secretory response and...
2.
Polster A, Perni S, Filipova D, Moua O, Ohrtman J, Bichraoui H, et al.
J Gen Physiol
. 2017 Dec;
150(2):293-306.
PMID: 29284662
The type 1 ryanodine receptor (RyR1) in skeletal muscle is a homotetrameric protein that releases Ca from the sarcoplasmic reticulum (SR) in response to an "orthograde" signal from the dihydropyridine...
3.
Ohrtman J, Romberg C, Moua O, Bannister R, Levinson S, Beam K
J Gen Physiol
. 2015 Mar;
145(4):303-14.
PMID: 25779869
CaV1.1 acts as both the voltage sensor that triggers excitation-contraction coupling in skeletal muscle and as an L-type Ca(2+) channel. It has been proposed that, after its posttranslational cleavage, the...
4.
Eltit J, Bannister R, Moua O, Altamirano F, Hopkins P, Pessah I, et al.
Proc Natl Acad Sci U S A
. 2012 May;
109(20):7923-8.
PMID: 22547813
Malignant hyperthermia (MH) susceptibility is a dominantly inherited disorder in which volatile anesthetics trigger aberrant Ca(2+) release in skeletal muscle and a potentially fatal rise in perioperative body temperature. Mutations...
5.
Sheridan D, Moua O, Lorenzon N, Beam K
Channels (Austin)
. 2012 Apr;
6(1):26-40.
PMID: 22522946
In skeletal muscle, L-type calcium channels (DHPRs), localized to plasma membrane sarcoplasmic reticulum junctions, are tightly packed into groups of four termed tetrads. Here, we have used bimolecular fluorescence complementation...
6.
Wenzlau J, Moua O, Sarkar S, Yu L, Rewers M, Eisenbarth G, et al.
Ann N Y Acad Sci
. 2009 Jan;
1150:256-9.
PMID: 19120307
Type 1A diabetes (T1D) results from autoimmunity targeted at a limited number of molecules that are expressed in the pancreatic beta cell. Putative novel autoantigen candidates were identified from microarray...
7.
Wenzlau J, Moua O, Liu Y, Eisenbarth G, Hutton J, Davidson H
Ann N Y Acad Sci
. 2009 Jan;
1150:252-5.
PMID: 19120306
The human zinc transporter Slc30A8 (ZnT8) is a major target of humoral autoimmunity in human type 1A diabetes. However, despite extensive conservation, the majority of human autoimmune sera fail to...
8.
Wenzlau J, Liu Y, Yu L, Moua O, Fowler K, Rangasamy S, et al.
Diabetes
. 2008 Jul;
57(10):2693-7.
PMID: 18591387
Objective: Zinc transporter eight (SLC30A8) is a major target of autoimmunity in human type 1A diabetes and is implicated in type 2 diabetes in genome-wide association studies. The type 2...
9.
Wenzlau J, Juhl K, Yu L, Moua O, Sarkar S, Gottlieb P, et al.
Proc Natl Acad Sci U S A
. 2007 Oct;
104(43):17040-5.
PMID: 17942684
Type 1 diabetes (T1D) results from progressive loss of pancreatic islet mass through autoimmunity targeted at a diverse, yet limited, series of molecules that are expressed in the pancreatic beta...
10.
Sarkar S, Wong R, Hackl S, Moua O, Gill R, Wiseman A, et al.
Diabetes
. 2006 Dec;
56(1):72-9.
PMID: 17192467
Indoleamine 2,3-dioxygenase (IDO) catalyzes the initial, rate-limiting step of tryptophan (Trp) catabolism along the kynurenine (KYN) pathway, and its induction in cells of the immune system in response to cytokines...