Om P S Patel
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Explore the profile of Om P S Patel including associated specialties, affiliations and a list of published articles.
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16
Citations
116
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Recent Articles
1.
Nandwana N, Patel O, Mehra M, Kumar A, Salvino J
Molecules
. 2024 May;
29(10).
PMID: 38792215
Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological...
2.
Ishrat N, Khan H, Patel O, Mahdi A, Mujeeb F, Ahmad S
Biomed Res Int
. 2021 Nov;
2021:7240046.
PMID: 34746307
The dysregulation of glucose metabolism that includes the modification of biomolecules with the help of glycation reaction results in the formation of advanced glycation end products (AGEs). The formation of...
3.
Patel O, Beteck R, Legoabe L
Eur J Med Chem
. 2021 Jan;
213:113193.
PMID: 33508479
Malaria is a life-threatening infectious disease caused by protozoal parasites belonging to the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria cases globally in 2018 as...
4.
Patel O, Beteck R, Legoabe L
Eur J Med Chem
. 2020 Dec;
210:113084.
PMID: 33333397
Atovaquone belongs to a naphthoquinone class of drugs and is used in combination with proguanil (Malarone) for the treatment of acute, uncomplicated malaria caused by Plasmodium falciparum (including chloroquine-resistant P. ...
5.
Patel O, Jesumoroti O, Legoabe L, Beteck R
Eur J Med Chem
. 2020 Nov;
210:112994.
PMID: 33234343
Nitroimidazoles based compounds remain a hot topic of research in medicinal chemistry due to their numerous biological activities. Moreover, many clinical candidates based on this chemical core have been reported...
6.
Patel O, Jaspal S, Shinde V, Nandwana N, Rangan K, Kumar A
J Org Chem
. 2020 May;
85(11):7309-7321.
PMID: 32408748
Phenyliodine(III) diacetate -mediated 1,2--migration of an imidazo[1,2-]pyridine ring via the formation of an aziridine intermediate in Mannich bases derived from imidazo[1,2-]pyridines, 2-pyridylamines or arylamines, and formaldehyde is reported. The imidazo[1,2-]pyridines...
7.
Nandwana N, Patel O, Srivathsa M, Kumar A
ACS Omega
. 2019 Aug;
4(6):10140-10150.
PMID: 31460106
A practical and efficient method has been developed for the dicarbonylation of imidazoheterocycles using glyoxals as dicarbonyl precursors under metal-free conditions in acetic acid. A series of symmetrical and unsymmetrical...
8.
Nandwana N, Singh R, Patel O, Dhiman S, Saini H, Jha P, et al.
ACS Omega
. 2019 Aug;
3(11):16338-16346.
PMID: 31458269
A new class of fused quinazolines has been designed and synthesized via copper-catalyzed Ullmann type C-N coupling followed by intramolecular cross-dehydrogenative coupling reaction in moderate to good yields. The synthesized...
9.
Patel O, Dhiman S, Khan S, Shinde V, Jaspal S, Srivathsa M, et al.
Org Biomol Chem
. 2019 Jun;
17(24):5962-5970.
PMID: 31157355
A simple and highly efficient strategy has been developed for the synthesis of 2-amidobenzoic acids through the tert-butyl hydroperoxide (TBHP)-mediated oxygenation and sequential ring opening of 2-arylindoles in a one-pot...
10.
Patel O, Arun A, Singh P, Saini D, Karade S, Chourasia M, et al.
Eur J Med Chem
. 2019 Feb;
167:226-244.
PMID: 30772606
A series of new pyranocarbazole derivatives were synthesized via semi-synthetic modification of koenimbine (1a) and koenidine (1b) isolated from the leaves of Murraya koenigii. Among all, compound 3bg displayed significant...