» Authors » Olivier Julien

Olivier Julien

Explore the profile of Olivier Julien including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 53
Citations 1129
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Delyea C, Forster M, Luo S, Dubrule B, Julien O, Bhavsar A
Biochemistry . 2024 Aug; 63(18):2266-2279. PMID: 39189508
As part of its pathogenesis, serovar Typhimurium delivers effector proteins into host cells. One effector is SspH2, a member of the so-called novel E3 ubiquitin ligase family, that interacts with...
2.
Gomez-Cardona E, Dehkordi M, Van Baar K, Vitkauskaite A, Julien O, Fearnhead H
Protein Sci . 2024 Aug; 33(9):e5156. PMID: 39180494
Executioner caspases, such as caspase-3, are known to induce apoptosis, but in other contexts, they can control very different fates, including cell differentiation and neuronal plasticity. While hundreds of caspase...
3.
Pirayeshfard L, Luo S, Githaka J, Saini A, Touret N, Goping I, et al.
J Proteome Res . 2024 Jul; 23(8):3433-3443. PMID: 38959414
Protein-protein interaction studies using proximity labeling techniques, such as biotin ligase-based BioID, have become integral in understanding cellular processes. Most studies utilize conventional 2D cell culture systems, potentially missing important...
4.
Eskandari-Sedighi G, Crichton M, Zia S, Gomez-Cardona E, Cortez L, Patel Z, et al.
Mol Neurodegener . 2024 May; 19(1):42. PMID: 38802940
Microglia play diverse pathophysiological roles in Alzheimer's disease (AD), with genetic susceptibility factors skewing microglial cell function to influence AD risk. CD33 is an immunomodulatory receptor associated with AD susceptibility...
5.
Beauchamp E, Gamma J, Cromwell C, Moussa E, Pain R, Kostiuk M, et al.
J Transl Med . 2024 May; 22(1):431. PMID: 38715059
Background: In humans, two ubiquitously expressed N-myristoyltransferases, NMT1 and NMT2, catalyze myristate transfer to proteins to facilitate membrane targeting and signaling. We investigated the expression of NMTs in numerous cancers...
6.
Hartley B, Bassiouni W, Roczkowsky A, Fahlman R, Schulz R, Julien O
J Proteome Res . 2024 Apr; 23(10):4188-4202. PMID: 38647137
Proteases are enzymes that induce irreversible post-translational modifications by hydrolyzing amide bonds in proteins. One of these proteases is matrix metalloproteinase-2 (MMP-2), which has been shown to modulate extracellular matrix...
7.
Alzahrani K, Gomez-Cardona E, Gandhi V, Palikhe N, Laratta C, Julien O, et al.
FASEB J . 2024 Mar; 38(5):e23531. PMID: 38466220
Inhaled aeroallergens can directly activate airway epithelial cells (AECs). Exposure to cockroach allergens is a strong risk factor for asthma. Cockroach allergens mediate some of their effects through their serine...
8.
Miranzadeh Mahabadi H, Lin Y, Ogando N, Moussa E, Mohammadzadeh N, Julien O, et al.
Proc Natl Acad Sci U S A . 2024 Feb; 121(8):e2315653121. PMID: 38346199
Monkeypox virus (MPXV) infections in humans cause neurological disorders while studies of MPXV-infected animals indicate that the virus penetrates the brain. Pyroptosis is an inflammatory type of regulated cell death,...
9.
Hartley B, Bassiouni W, Roczkowsky A, Fahlman R, Schulz R, Julien O
J Proteome Res . 2024 Jan; 23(2):844-856. PMID: 38264990
Myocardial ischemia-reperfusion (IR) (stunning) injury triggers changes in the proteome and degradome of the heart. Here, we utilize quantitative proteomics and comprehensive degradomics to investigate the molecular mechanisms of IR...
10.
Gomez-Cardona E, Eskandari-Sedighi G, Fahlman R, Westaway D, Julien O
ACS Chem Neurosci . 2023 Dec; 15(1):134-146. PMID: 38095594
Alternative α- and β-cleavage events in the cellular prion protein (PrP) central region generate fragments with distinct biochemical features that affect prion disease pathogenesis, but the assignment of precise cleavage...