Oleg Yegorov
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Explore the profile of Oleg Yegorov including associated specialties, affiliations and a list of published articles.
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12
Citations
158
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Recent Articles
1.
Yang C, Trivedi V, Dyson K, Gu T, Candelario K, Yegorov O, et al.
Genome Med
. 2024 Aug;
16(1):102.
PMID: 39160595
Background: The current standard of care treatments for medulloblastoma are insufficient as these do not take tumor heterogeneity into account. Newer, safer, patient-specific treatment approaches are required to treat high-risk...
2.
von Roemeling C, Patel J, Carpenter S, Yegorov O, Yang C, Bhatia A, et al.
Nat Commun
. 2024 Jul;
15(1):5871.
PMID: 38997283
There are numerous mechanisms by which glioblastoma cells evade immunological detection, underscoring the need for strategic combinatorial treatments to achieve appreciable therapeutic effects. However, developing combination therapies is difficult due...
3.
Trivedi V, Yang C, Klippel K, Yegorov O, von Roemeling C, Hoang-Minh L, et al.
Genome Med
. 2024 Jan;
16(1):17.
PMID: 38268001
Background: Despite advancements in the successful use of immunotherapy in treating a variety of solid tumors, applications in treating brain tumors have lagged considerably. This is due, at least in...
4.
von Roemeling C, Yegorov O, Yang C, Klippel K, Russell R, Trivedi V, et al.
Res Sq
. 2023 Nov;
PMID: 38014191
The promise of immunotherapy to induce long-term durable responses in conventionally treatment resistant tumors like glioblastoma (GBM) has given hope for patients with a dismal prognosis. Yet, few patients have...
5.
DiVita Dean B, Wildes T, Dean J, Yegorov O, Yang C, Shin D, et al.
J Immunother Cancer
. 2023 Feb;
11(2).
PMID: 36750252
Background: Glioma-induced immune dysregulation of the hematopoietic system has been described in a limited number of studies. In this study, our group further demonstrates that gliomas interrupt the cellular differentiation...
6.
Yegorova S, Yegorov O, Ferreira L
Gene
. 2020 Dec;
770:145356.
PMID: 33333219
The diaphragm is the main inspiratory muscle, and the chronic phase post-myocardial infarction (MI) is characterized by diaphragm morphological, contractile, and metabolic abnormalities. However, the mechanisms of diaphragm weakness are...
7.
Wildes T, Dyson K, Francis C, Wummer B, Yang C, Yegorov O, et al.
Clin Cancer Res
. 2020 Aug;
26(21):5689-5700.
PMID: 32788225
Purpose: Immunotherapy has been demonstrably effective against multiple cancers, yet tumor escape is common. It remains unclear how brain tumors escape immunotherapy and how to overcome this immune escape. Experimental...
8.
Evans V, Kumar N, Filali A, Procopio F, Yegorov O, Goulet J, et al.
PLoS Pathog
. 2013 Dec;
9(12):e1003799.
PMID: 24339779
Latently infected resting CD4(+) T cells are a major barrier to HIV cure. Understanding how latency is established, maintained and reversed is critical to identifying novel strategies to eliminate latently...
9.
Doroudchi M, Yegorov O, Baumgartner T, Kernaleguen A, Breton G, Ndongala M, et al.
PLoS One
. 2012 Nov;
7(11):e49562.
PMID: 23185362
Objective: To determine the function and phenotype of CD8(+) T-cells targeting consensus and autologous sequences of entire HIV-1 Nef protein. Methods: Multiparameter flow cytometry-based analysis was used to evaluate the...
10.
Routy J, Boulassel M, Yassine-Diab B, Nicolette C, Healey D, Jain R, et al.
Clin Immunol
. 2009 Nov;
134(2):140-7.
PMID: 19889582
Immunogenicity, manufacturing feasibility, and safety of a novel, autologous dendritic cell (DC)-based immunotherapy (AGS-004) was evaluated in ten human immunodeficiency virus type 1 (HIV-1)-infected adults successfully treated with antiretroviral therapy...