Oleg Butovsky
Overview
Explore the profile of Oleg Butovsky including associated specialties, affiliations and a list of published articles.
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82
Citations
12387
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Recent Articles
1.
Izzy S, Yahya T, Albastaki O, Abou-El-Hassan H, Aronchik M, Cao T, et al.
Nat Neurosci
. 2025 Feb;
28(3):499-516.
PMID: 40016353
Neuroinflammation plays a crucial role in traumatic brain injury (TBI), contributing to both damage and recovery, yet no effective therapy exists to mitigate central nervous system (CNS) injury and promote...
2.
Brandao W, Jain N, Yin Z, Kleemann K, Carpenter M, Bao X, et al.
Sci Transl Med
. 2025 Jan;
17(781):eadk3690.
PMID: 39813317
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder. Antiamyloid antibody treatments modestly slow disease progression in mild dementia due to AD. Emerging evidence shows that homeostatic dysregulation of the...
3.
Yin Z, Leonard A, Porto C, Xie Z, Silveira S, Culley D, et al.
J Neuroinflammation
. 2024 Dec;
21(1):323.
PMID: 39696348
Background: Microglia, the resident immune cells of the brain, play a crucial role in maintaining homeostasis in the central nervous system (CNS). However, they can also contribute to neurodegeneration through...
4.
Heneka M, van der Flier W, Jessen F, Hoozemanns J, Thal D, Boche D, et al.
Nat Rev Immunol
. 2024 Dec;
PMID: 39653749
Increasing evidence points to a pivotal role of immune processes in the pathogenesis of Alzheimer disease, which is the most prevalent neurodegenerative and dementia-causing disease of our time. Multiple lines...
5.
Bosch M, Dodiya H, Michalkiewicz J, Lee C, Shaik S, Weigle I, et al.
Mol Neurodegener
. 2024 Oct;
19(1):70.
PMID: 39390529
No abstract available.
6.
Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, et al.
Nat Neurosci
. 2024 Aug;
27(9):1858-1859.
PMID: 39143410
No abstract available.
7.
Rosenzweig N, Kleemann K, Rust T, Carpenter M, Grucci M, Aronchik M, et al.
Nat Med
. 2024 Jul;
30(10):2990-3003.
PMID: 38961225
APOE4 is the strongest genetic risk factor for Alzheimer's disease (AD), with increased odds ratios in female carriers. Targeting amyloid plaques shows modest improvement in male non-APOE4 carriers. Leveraging single-cell...
8.
Kaiser T, Dattero J, Li L, Chen M, Jiang M, Harrahill A, et al.
eNeuro
. 2024 Jun;
11(7).
PMID: 38926085
Microglia carry out important functions as the resident macrophages of the brain. To study their role in health and disease, the research community needs tools to genetically modify them with...
9.
Wasen C, Beauchamp L, Vincentini J, Li S, S LeServe D, Gauthier C, et al.
Nat Commun
. 2024 May;
15(1):3872.
PMID: 38719797
The gut microbiota and microglia play critical roles in Alzheimer's disease (AD), and elevated Bacteroides is correlated with cerebrospinal fluid amyloid-β (Aβ) and tau levels in AD. We hypothesize that...
10.
Bosch M, Dodiya H, Michalkiewicz J, Lee C, Shaik S, Weigle I, et al.
Mol Neurodegener
. 2024 Feb;
19(1):18.
PMID: 38365827
It has recently become well-established that there is a connection between Alzheimer's disease pathology and gut microbiome dysbiosis. We have previously demonstrated that antibiotic-mediated gut microbiota perturbations lead to attenuation...