Nikolas K Haass
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Explore the profile of Nikolas K Haass including associated specialties, affiliations and a list of published articles.
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85
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2968
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Recent Articles
1.
Raut S, Joly F, Haass N, Eri R, Canales J, Benedek D, et al.
Transl Psychiatry
. 2024 Dec;
14(1):492.
PMID: 39695081
This study establishes mirdametinib as the first MEK inhibitor that can undergo clinical development for psychiatric indications such as post-traumatic stress disorder (PTSD). PTSD is characterized by persistent traumatic memories...
2.
Ju R, Falconer A, Schmidt C, Enriquez Martinez M, Dean K, Fiolka R, et al.
Nat Cell Biol
. 2024 Aug;
26(9):1520-1534.
PMID: 39160291
Cells migrating through complex three-dimensional environments experience considerable physical challenges, including tensile stress and compression. To move, cells need to resist these forces while also squeezing the large nucleus through...
3.
Malekan M, Haass N, Rokni G, Gholizadeh N, Ebrahimzadeh M, Kazeminejad A
Life Sci
. 2024 Mar;
345:122563.
PMID: 38508233
Melanoma is responsible for most skin cancer-associated deaths globally. The progression of melanoma is influenced by a number of pathogenic processes. Understanding the VEGF/VEGFR axis, which includes VEGF-A, PlGF, VEGF-B,...
4.
Spoerri L, Beaumont K, Anfosso A, Murphy R, Browning A, Gunasingh G, et al.
Methods Mol Biol
. 2024 Feb;
2764:291-310.
PMID: 38393602
Aberrant cell cycle progression is a hallmark of solid tumors. Therefore, cell cycle analysis is an invaluable technique to study cancer cell biology. However, cell cycle progression has been most...
5.
Ke Y, van Hummel A, Au C, Chan G, Lee W, van der Hoven J, et al.
Neuron
. 2024 Feb;
112(8):1249-1264.e8.
PMID: 38366598
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are characterized by cytoplasmic deposition of the nuclear TAR-binding protein 43 (TDP-43). Although cytoplasmic re-localization of TDP-43 is a key event in...
6.
Murphy R, Gunasingh G, Haass N, Simpson M
Bull Math Biol
. 2023 Dec;
86(1):8.
PMID: 38091169
Co-culture tumour spheroid experiments are routinely performed to investigate cancer progression and test anti-cancer therapies. Therefore, methods to quantitatively characterise and interpret co-culture spheroid growth are of great interest. However,...
7.
Ravindran Menon D, Hammerlindl H, Gimenez G, Hammerlindl S, Zuegner E, Torrano J, et al.
Drug Resist Updat
. 2023 Aug;
71:100993.
PMID: 37639774
Aims: Drivers of the drug tolerant proliferative persister (DTPP) state have not been well investigated. Histone H3 lysine-4 trimethylation (H3K4me3), an active histone mark, might enable slow cycling drug tolerant...
8.
Wallingford C, Demeshko A, Krishnakripa A, Smit D, Duffy D, Betz-Stablein B, et al.
Br J Dermatol
. 2023 Mar;
188(6):770-776.
PMID: 36879448
Background: Population-wide screening for melanoma is not cost-effective, but genetic characterization could facilitate risk stratification and targeted screening. Common Melanocortin-1 receptor (MC1R) red hair colour (RHC) variants and Microphthalmia-associated transcription...
9.
Basnayake B, Leo P, Rao S, Vasani S, Kenny L, Haass N, et al.
Br J Cancer
. 2023 Feb;
128(10):1807-1818.
PMID: 36765173
Head and neck cancers (HNC) are the seventh most prevalent cancer type globally. Despite their common categorisation, HNCs are a heterogeneous group of malignancies arising in various anatomical sites within...
10.
Murphy R, Gunasingh G, Haass N, Simpson M
PLoS Comput Biol
. 2023 Jan;
19(1):e1010833.
PMID: 36634128
Tumours are subject to external environmental variability. However, in vitro tumour spheroid experiments, used to understand cancer progression and develop cancer therapies, have been routinely performed for the past fifty...