Nikita Malik
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Explore the profile of Nikita Malik including associated specialties, affiliations and a list of published articles.
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10
Citations
50
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Recent Articles
1.
Shukla S, Bhattacharya A, Sehrawat P, Agarwal P, Shobhawat R, Malik N, et al.
Structure
. 2024 Apr;
32(6):690-705.e6.
PMID: 38565139
The centromere is epigenetically marked by a histone H3 variant-CENP-A. The budding yeast CENP-A called Cse4, consists of an unusually long N-terminus that is known to be involved in kinetochore...
2.
Dubey R, Kulkarni S, Dantu S, Panigrahi R, Sardesai D, Malik N, et al.
Biol Chem
. 2021 Feb;
402(2):179-194.
PMID: 33544469
The aberrant misfolding and self-assembly of human islet amyloid polypeptide (hIAPP)-a hormone that is co-secreted with insulin from pancreatic β-cells-into toxic oligomers, protofibrils and fibrils has been observed in type...
3.
Balakrishnan A, Malik N
Intervirology
. 2020 Dec;
:1-4.
PMID: 33321508
Chandipura virus (CHPV) is a tropical pathogen, suggesting its involvement in childhood encephalitis syndrome in India. No reports are available in adult human beings for its pathogenicity. Similarly, in adult...
4.
Malik N, Wahlbeck K, Thompson L
Biochim Biophys Acta Biomembr
. 2020 Apr;
1862(9):183312.
PMID: 32304758
Bacterial chemoreceptors are organized in arrays composed of helical receptors arranged as trimers of dimers, coupled to a histidine kinase CheA and a coupling protein CheW. Ligand binding to the...
5.
Kashefi M, Malik N, Struppe J, Thompson L
J Magn Reson
. 2019 Jun;
305:5-15.
PMID: 31158793
Protein dynamics play key mechanistic roles but are difficult to measure in large proteins and protein complexes. INEPT and CP solid-state NMR experiments have often been used to obtain spectra...
6.
Dubey R, Patil K, Dantu S, Sardesai D, Bhatia P, Malik N, et al.
Biochem J
. 2019 Mar;
476(5):889-907.
PMID: 30814273
The human islet amyloid polypeptide (hIAPP) or amylin is the major constituent of amyloidogenic aggregates found in pancreatic islets of type 2 diabetic patients that have been associated with β-cell...
7.
Malik N, Dantu S, Shukla S, Kombrabail M, Ghosh S, Krishnamoorthy G, et al.
J Biol Chem
. 2018 Nov;
293(52):20273-20284.
PMID: 30381395
The histone variant CENP-A is a core component of the specialized nucleosome at the centromere in budding yeast and is required for genomic integrity. Accordingly, the levels of Cse4 in...
8.
Dubey R, Minj P, Malik N, Sardesai D, Kulkarni S, Acharya J, et al.
Biochem J
. 2017 Oct;
474(23):3915-3934.
PMID: 29046394
Protein misfolding and aggregation play an important role in many human diseases including Alzheimer's, Parkinson's and type 2 diabetes mellitus (T2DM). The human islet amyloid polypeptide (hIAPP) forms amyloid plaques...
9.
Malik N, Kumar A
J Biomol NMR
. 2016 Sep;
66(1):21-35.
PMID: 27586017
NMR resonance assignment of intrinsically disordered proteins poses a challenge because of the limited dispersion of amide proton chemical shifts. This becomes even more complex with the increase in the...
10.
Malik N, Naik D, Uppoor A
Implant Dent
. 2015 May;
24(4):434-40.
PMID: 25996788
Purpose: The study evaluated 2 biomarkers (myeloperoxidase [MPO] and alkaline phosphatase) along with clinical parameters in periimplant sulcus fluid (PISF) in conditions of periimplant health and disease. The effect of...