Jhankar D Acharya
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Explore the profile of Jhankar D Acharya including associated specialties, affiliations and a list of published articles.
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9
Citations
147
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Recent Articles
1.
Dubey R, Kulkarni S, Dantu S, Panigrahi R, Sardesai D, Malik N, et al.
Biol Chem
. 2021 Feb;
402(2):179-194.
PMID: 33544469
The aberrant misfolding and self-assembly of human islet amyloid polypeptide (hIAPP)-a hormone that is co-secreted with insulin from pancreatic β-cells-into toxic oligomers, protofibrils and fibrils has been observed in type...
2.
Malik S, Acharya J, Mehendale N, Kamat S, Ghaskadbi S
Free Radic Res
. 2019 Jun;
53(7):815-827.
PMID: 31223033
Insulin resistance (IR) is known to precede onset of type 2 diabetes and increased oxidative stress appears to be a deleterious factor leading to IR. In this study, we evaluated...
3.
Yousf S, Sardesai D, Mathew A, Khandelwal R, Acharya J, Sharma S, et al.
Metabolomics
. 2019 Mar;
15(4):55.
PMID: 30927092
Introduction: Chronic exposure to high-glucose and free fatty acids (FFA) alone/or in combination; and the resulting gluco-, lipo- and glucolipo-toxic conditions, respectively, have been known to induce dysfunction and apoptosis...
4.
Dubey R, Patil K, Dantu S, Sardesai D, Bhatia P, Malik N, et al.
Biochem J
. 2019 Mar;
476(5):889-907.
PMID: 30814273
The human islet amyloid polypeptide (hIAPP) or amylin is the major constituent of amyloidogenic aggregates found in pancreatic islets of type 2 diabetic patients that have been associated with β-cell...
5.
Dubey R, Minj P, Malik N, Sardesai D, Kulkarni S, Acharya J, et al.
Biochem J
. 2017 Oct;
474(23):3915-3934.
PMID: 29046394
Protein misfolding and aggregation play an important role in many human diseases including Alzheimer's, Parkinson's and type 2 diabetes mellitus (T2DM). The human islet amyloid polypeptide (hIAPP) forms amyloid plaques...
6.
Karamshetty V, Acharya J, Ghaskadbi S, Goel P
Front Cell Dev Biol
. 2016 Apr;
4:16.
PMID: 27047940
Deficiencies in vitamin B12 and glutathione (GSH) are associated with a number of diseases including type 2 diabetes mellitus. We tested newly diagnosed Indian diabetic patients for correlation between their...
7.
Acharya J, Pande A, Joshi S, Yajnik C, Ghaskadbi S
Diabetes Metab Res Rev
. 2014 Jan;
30(7):590-8.
PMID: 24459082
Background: There exist several reports demonstrating enhancement in oxidative stress in diabetic patients; however, serial and comprehensive measurement of oxidative stress parameters in newly diagnosed diabetic patients is not yet...
8.
Acharya J, Ghaskadbi S
BMC Complement Altern Med
. 2013 Sep;
13:238.
PMID: 24070177
Background: Pterostilbene, a methoxylated analog of Resveratrol, is gradually gaining more importance as a therapeutic drug owing to its higher lipophilicity, bioavailability and biological activity than Resveratrol. This study was...
9.
Acharya J, Ghaskadbi S
Islets
. 2010 Nov;
2(4):225-35.
PMID: 21099317
Pancreatic β-cells secrete insulin in response to changes in extracellular glucose concentration. Persistent hyperglycemia during diabetes exerts toxic effects on islets by creating redox imbalance arising from overproduction of reactive...