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Niharika A Duggal

Explore the profile of Niharika A Duggal including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 492
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Recent Articles
11.
Clegg M, Methven L, Lanham-New S, Green M, Duggal N, Hetherington M
Nutr Bull . 2023 Jan; 48(1):124-133. PMID: 36718711
By 2050, it is predicted that one in four people in the United Kingdom will be aged 65 years and over. Increases in lifespan are not always translated into years...
12.
Foster M, Bentley C, Hazeldine J, Acharjee A, Nahman O, Shen-Orr S, et al.
Immun Ageing . 2022 Dec; 19(1):60. PMID: 36471343
Background: Traumatic injury elicits a hyperinflammatory response and remodelling of the immune system leading to immuneparesis. This study aimed to evaluate whether traumatic injury results in a state of prematurely...
13.
Taylor J, Greenhaff P, Bartlett D, Jackson T, Duggal N, Lord J
Physiol Rev . 2022 Oct; 103(2):1137-1191. PMID: 36239451
"Frailty" is a term used to refer to a state characterized by enhanced vulnerability to, and impaired recovery from, stressors compared with a nonfrail state, which is increasingly viewed as...
14.
Monaghan T, Duggal N, Rosati E, Griffin R, Hughes J, Roach B, et al.
Cells . 2021 Nov; 10(11). PMID: 34831456
Fecal microbiota transplantation (FMT) is highly effective in recurrent infection (CDI); increasing evidence supports FMT in severe or fulminant infection (SFCDI). However, the multifactorial mechanisms that underpin the efficacy of...
15.
Conway J, Certo M, Lord J, Mauro C, Duggal N
Br J Pharmacol . 2021 Aug; 179(9):1808-1824. PMID: 34435354
Advancing age is accompanied by significant remodelling of the immune system, termed immune senescence, and increased systemic inflammation, termed inflammageing, both of which contribute towards an increased risk of developing...
16.
Conway J, Duggal N
Ageing Res Rev . 2021 Mar; 68:101323. PMID: 33771720
Advancing age is accompanied by changes in the gut microbiota characterised by a loss of beneficial commensal microbes that is driven by intrinsic and extrinsic factors such as diet, medications,...
17.
Tomic A, Tomic I, Waldron L, Geistlinger L, Kuhn M, Spreng R, et al.
Patterns (N Y) . 2021 Jan; 2(1):100178. PMID: 33511368
Data analysis and knowledge discovery has become more and more important in biology and medicine with the increasing complexity of biological datasets, but the necessarily sophisticated programming skills and in-depth...
18.
Bartlett D, Duggal N
Age Ageing . 2020 Mar; 49(3):368-373. PMID: 32221610
Introduction: ageing is accompanied by impairments in immune responses due to remodelling of the immune system (immunesenescence). Additionally, a decline in habitual physical activity has been reported in older adults....
19.
Duggal N, Niemiro G, Harridge S, Simpson R, Lord J
Nat Rev Immunol . 2019 Jun; 19(9):563-572. PMID: 31175337
Remodelling of the immune system with age - immunosenescence - is a substantial contributor to poor health in older adults, with increasing risk of infections, cancer and chronic inflammatory disease...
20.
Duggal N
Biogerontology . 2018 Oct; 19(6):481-496. PMID: 30269199
It is widely accepted that ageing is accompanied by remodelling of the immune system, including reduced numbers of naïve T cells, increased senescent or exhausted T cells, compromise to monocyte,...