Nigel J Walker
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Explore the profile of Nigel J Walker including associated specialties, affiliations and a list of published articles.
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69
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1503
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Recent Articles
1.
Hamm J, Hsieh J, Roberts G, Collins B, Gorospe J, Sparrow B, et al.
Toxics
. 2024 Jan;
12(1).
PMID: 38276729
Embryonic zebrafish represent a useful test system to screen substances for their ability to perturb development. The exposure scenarios, endpoints captured, and data analysis vary among the laboratories who conduct...
2.
Ihrie M, Taylor-Just A, Walker N, Stout M, Gupta A, Richey J, et al.
Inhal Toxicol
. 2019 Jul;
31(5):192-202.
PMID: 31345048
Increasing evidence from rodent studies indicates that inhaled multi-walled carbon nanotubes (MWCNTs) have harmful effects on the lungs. In this study, we examined the effects of inhalation exposure to MWCNTs...
3.
Galli C, Walker N, Oberlies N, Roe A, Edwards J, Fitzpatrick S, et al.
Toxicol Lett
. 2019 May;
314:10-17.
PMID: 31082523
Botanical safety science continues to evolve as new tools for risk assessment become available alongside continual desire by consumers for "natural" botanical ingredients in consumer products. Focusing on botanical food/dietary...
4.
Using Tox21 High-Throughput Screening Assays for the Evaluation of Botanical and Dietary Supplements
Hubbard T, Hsieh J, Rider C, Sipes N, Sedykh A, Collins B, et al.
Appl In Vitro Toxicol
. 2019 Apr;
5(1):10-25.
PMID: 30944845
Recent nationwide surveys found that natural products, including botanical dietary supplements, are used by ∼18% of adults. In many cases, there is a paucity of toxicological data available for these...
5.
Behl M, Ryan K, Hsieh J, Parham F, Shapiro A, Collins B, et al.
Toxicol Sci
. 2018 Nov;
167(1):6-14.
PMID: 30496580
The National Toxicology Program (NTP) receives requests to evaluate chemicals with potential to cause adverse health effects, including developmental neurotoxicity (DNT). Some recent requests have included classes of chemicals such...
6.
Hamm J, Ceger P, Allen D, Stout M, Maull E, Baker G, et al.
ALTEX
. 2018 Nov;
36(1):103-120.
PMID: 30415271
There is a need for fast, efficient, and cost-effective hazard identification and characterization of chemical hazards. This need is generating increased interest in the use of zebrafish embryos as both...
7.
Pettibone K, Balshaw D, Dilworth C, Drew C, Hall J, Heacock M, et al.
Environ Health Perspect
. 2018 Jul;
126(7):074501.
PMID: 30024381
The National Institute of Environmental Health Sciences (NIEHS) introduces a new translational research framework that builds upon previous biomedical models to create a more comprehensive and integrated environmental health paradigm....
8.
Rider C, Walker N, Waidyanatha S
Clin Pharmacol Ther
. 2018 May;
104(3):429-431.
PMID: 29745419
The National Toxicology Program's (NTP) mission is "to evaluate agents of public health concern, by developing and applying the tools of modern toxicology and molecular biology." Botanical dietary supplements (BDS)...
9.
Shipkowski K, Betz J, Birnbaum L, Bucher J, Coates P, Hopp D, et al.
Food Chem Toxicol
. 2018 Apr;
118:963-971.
PMID: 29626579
Due to the extensive use of botanical dietary supplements by consumers in the United States, there is a need for appropriate research and data to support safety assessments. Complexity and...
10.
Gao L, Mutlu E, Collins L, Walker N, Hartwell H, Olson J, et al.
Chem Res Toxicol
. 2017 Feb;
30(3):794-803.
PMID: 28207250
DNA oxidation damage has been regarded as one of the possible mechanisms for the hepatic carcinogenesis of dioxin-like compounds (DLCs). In this study, we evaluated the toxic equivalency factor (TEF)...