Nigel J Jones
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Explore the profile of Nigel J Jones including associated specialties, affiliations and a list of published articles.
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24
Citations
503
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Recent Articles
1.
Edogbanya J, Tejada-Martinez D, Jones N, Jaiswal A, Bell S, Cordeiro R, et al.
Cell Mol Life Sci
. 2021 Feb;
78(9):4365-4376.
PMID: 33625522
The C1ORF112 gene initially drew attention when it was found to be strongly co-expressed with several genes previously associated with cancer and implicated in DNA repair and cell cycle regulation,...
2.
Ferguson F, McLennan A, Urbaniak M, Jones N, Copeland N
Front Mol Biosci
. 2020 Dec;
7:606807.
PMID: 33282915
Cellular homeostasis requires adaption to environmental stress. In response to various environmental and genotoxic stresses, all cells produce dinucleoside polyphosphates (NpNs), the best studied of which is diadenosine tetraphosphate (ApA)....
3.
Paredes R, Kelly J, Geary B, Almarzouq B, Schneider M, Pearson S, et al.
Cell Death Dis
. 2020 Oct;
11(10):878.
PMID: 33082307
The transcriptional regulator EVI1 has an essential role in early development and haematopoiesis. However, acute myeloid leukaemia (AML) driven by aberrantly high EVI1 expression has very poor prognosis. To investigate...
4.
Marriott A, Vasieva O, Fang Y, Copeland N, McLennan A, Jones N
PLoS One
. 2016 May;
11(5):e0154674.
PMID: 27144453
Regulation of gene expression is one of several roles proposed for the stress-induced nucleotide diadenosine tetraphosphate (Ap4A). We have examined this directly by a comparative RNA-Seq analysis of KBM-7 chronic...
5.
Marriott A, Copeland N, Cunningham R, Wilkinson M, McLennan A, Jones N
DNA Repair (Amst)
. 2015 Jul;
33:90-100.
PMID: 26204256
The level of intracellular diadenosine 5', 5'''-P(1),P(4)-tetraphosphate (Ap4A) increases several fold in mammalian cells treated with non-cytotoxic doses of interstrand DNA-crosslinking agents such as mitomycin C. It is also increased...
6.
Chen X, Wilson J, McChesney P, Williams S, Kwon Y, Longerich S, et al.
J Biol Chem
. 2014 Jul;
289(37):25774-82.
PMID: 25070891
Fanconi anemia is a genetic disease resulting in bone marrow failure, birth defects, and cancer that is thought to encompass a defect in maintenance of genomic stability. Mutations in 16...
7.
Jones N
Methods Mol Biol
. 2011 Dec;
817:183-206.
PMID: 22147574
32P-postlabelling is a technique originally described by Kurt Randerath and colleagues for the sensitive detection of damage produced in DNA by reactive chemicals or genotoxins. The procedure essentially entails the...
8.
Wu J, Jones N
Methods Mol Biol
. 2011 Dec;
817:165-81.
PMID: 22147573
The single cell gel electrophoresis (SCGE) assay, more commonly known as the comet assay, due to the "comet-like" appearance of the cells, was originally developed as a technique to measure...
9.
Williams S, Wilson J, Clark A, Mitson-Salazar A, Tomashevski A, Ananth S, et al.
Hum Mol Genet
. 2011 Aug;
20(22):4395-410.
PMID: 21865299
Fanconi anemia (FA) is a rare genetic disorder characterized by bone marrow failure and an increased risk for leukemia and cancer. Fifteen proteins thought to function in the repair of...
10.
de Silva Rudland S, Platt-Higgins A, Winstanley J, Jones N, Barraclough R, West C, et al.
Am J Pathol
. 2011 Aug;
179(2):1061-72.
PMID: 21801876
Two subgroups of invasive breast carcinomas have been identified with a poor prognosis in different patient cohorts: the basal-like category and the subgroup containing proteins capable of inducing metastasis in...