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Nigel Brown

Explore the profile of Nigel Brown including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 156
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Recent Articles
1.
Srinivasan S, Kryza T, Bock N, Tse B, Sokolowski K, Janaththani P, et al.
Nat Commun . 2024 Nov; 15(1):9587. PMID: 39505858
Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA)...
2.
Srinivasan S, Kryza T, Bock N, Tse B, Sokolowski K, Panchadsaram J, et al.
Res Sq . 2023 Apr; PMID: 37034758
Genetic variation at the 19q13.3 locus is linked with prostate cancer susceptibility. The non-synonymous SNP, rs17632542 (c.536T>C; Ile163Thr-substitution in PSA) is associated with reduced prostate cancer risk, however, the functional...
3.
Hayes D, Morgan H, Brown N
Heart . 2020 Nov; 106(24):1926-1952. PMID: 33243785
No abstract available.
4.
Nolan B, Sorbello J, Brown N, Dimeski G, Inder W
Endocrine . 2018 Jan; 59(3):520-528. PMID: 29299794
Purpose: The ACTH stimulation test is commonly used to assess the hypothalamic-pituitary-adrenal (HPA) axis. Given variations in CBG concentration and binding affinity, serum total cortisol may misclassify some patients. Salivary...
5.
Lyons O, Saha P, Seet C, Kuchta A, Arnold A, Grover S, et al.
J Exp Med . 2017 Jul; 214(8):2437-2452. PMID: 28724617
Venous valves (VVs) prevent venous hypertension and ulceration. We report that FOXC2 and GJC2 mutations are associated with reduced VV number and length. In mice, early VV formation is marked...
6.
Dimeski G, Johnston J, Masci P, Zhao K, Brown N
Clin Chem Lab Med . 2017 Jan; 55(8):1135-1141. PMID: 28076307
Background: Current commercial tubes have difficulties in producing "true" serum from all blood samples even within the recommended clotting times. Hence, Becton Dickinson (BD) and now Greiner have produced tubes...
7.
Watts K, Fuentes-Montemayor E, Macgregor N, Peredo-Alvarez V, Ferryman M, Bellamy C, et al.
Ecol Evol . 2016 May; 6(9):3012-25. PMID: 27217949
Natural experiments have been proposed as a way of complementing manipulative experiments to improve ecological understanding and guide management. There is a pressing need for evidence from such studies to...
8.
Dimeski G, Bassett K, Brown N
Biochem Med (Zagreb) . 2015 Feb; 25(1):117-24. PMID: 25672475
Introduction: Gentamicin due to its low level of resistance and rapid bactericidal activity is commonly used to treat gram-negative bacteria. However, due to its toxic effects it needs to be...
9.
Dimeski G, Coogan M, Jones B, Brown N
Clin Chem Lab Med . 2014 Sep; 53(4):e101-3. PMID: 25257160
No abstract available.
10.
Slack A, Tredger M, Brown N, Corcoran B, Moore K
Ann Clin Biochem . 2013 Jul; 51(Pt 1):80-8. PMID: 23847035
Background: Glomerular filtration rate (GFR) and mortality is more accurately determined by gold standard measures than serum creatinine-based estimates in cirrhosis. No formal validation of any gold standard method has...