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Lorelei A Mucci

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Articles 363
Citations 11566
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Recent Articles
1.
Mitchell J, Camacho N, Shea P, Stopsack K, Joseph V, Burren O, et al.
Nat Commun . 2025 Feb; 16(1):1779. PMID: 39971927
To assess the contribution of rare coding germline genetic variants to prostate cancer risk and severity, we perform here a meta-analysis of 37,184 prostate cancer cases and 331,329 male controls...
2.
McGrath C, Shreves A, Shanahan M, Guard H, Nhliziyo M, Pernar C, et al.
Int J Cancer . 2024 Dec; PMID: 39663641
The most common somatic alteration in primary prostate cancer is the TMPRSS2:ERG gene fusion, which may be caused or promoted by distinct etiologic factors. The objective of this systematic review...
3.
Srinivasan S, Kryza T, Bock N, Tse B, Sokolowski K, Janaththani P, et al.
Nat Commun . 2024 Nov; 15(1):9587. PMID: 39505858
Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA)...
4.
Oh W, Agarwal N, Bryce A, Barata P, Bugler C, Carlsson S, et al.
Eur Urol . 2024 Oct; 87(2):101-103. PMID: 39472202
Much of the disease nomenclature used for patients with advanced prostate cancer has negative connotations and can be confusing or intimidating. Experts in the field convened to recommend a clearer...
5.
Stopsack K, Vijai J, Conry M, Berchuck J, Kemel Y, Vasselman S, et al.
Clin Cancer Res . 2024 Oct; 31(1):122-129. PMID: 39450704
Purpose: Deleterious germline variants in certain DNA repair genes are risk factors for developing aggressive prostate cancer. The objective was to quantify their prognostic impact after prostate cancer diagnosis. Experimental...
6.
Su X, Stopsack K, Schmidt D, Ma D, Li Z, Scheet P, et al.
Proc Natl Acad Sci U S A . 2024 Aug; 121(36):e2405543121. PMID: 39190349
Higher levels of aneuploidy, characterized by imbalanced chromosome numbers, are associated with lethal progression in prostate cancer. However, how aneuploidy contributes to prostate cancer aggressiveness remains poorly understood. In this...
7.
Chen N, Hu C, Iyer H, James P, Dickerman B, Mucci L, et al.
Environ Res . 2024 Aug; 262(Pt 1):119847. PMID: 39187150
Introduction: Neighborhood greenness may benefit long-term prostate cancer survivorship by promoting physical activity and social integration, and reducing stress and exposure to air pollution, noise, and extreme temperatures. We examined...
8.
Vaselkiv J, Shui I, Grob S, Ericsson C, Giovannucci I, Peng C, et al.
Carcinogenesis . 2024 Aug; 45(10):735-744. PMID: 39120256
High circulating vitamin D levels and supplementation may lower prostate cancer mortality. To probe for direct effects of vitamin D signaling in the primary tumor, we assessed how activation of...
9.
Zhang Y, Song M, Wang M, Hertzmark E, Wu K, Eliassen A, et al.
J Intern Med . 2024 Jul; 296(3):260-279. PMID: 39021307
Background: Evidence on type 2 diabetes onset age and duration on mortality risk has been limited by short follow-up, inadequate control for confounding, missing repeated measurements, and inability to cover...
10.
Guo F, McGee E, Chiu Y, Giovannucci E, Mucci L, Dickerman B
Am J Epidemiol . 2024 Jul; 194(2):449-459. PMID: 38973750
The 2018 World Cancer Research Fund/American Institute for Cancer Research recommends sustained strategies of physical activity and diet for cancer prevention, but evidence for long-term prostate cancer risk is limited....