Nicole P Kasica
Overview
Explore the profile of Nicole P Kasica including associated specialties, affiliations and a list of published articles.
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6
Citations
160
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Recent Articles
1.
Kasica N, Zhou X, Jester H, Holland C, Ryazanov A, Forshaw T, et al.
Front Aging Neurosci
. 2022 Sep;
14:959326.
PMID: 36158543
Maintenance of memory and synaptic plasticity depends on protein synthesis, and accumulating evidence implicates a role of dysregulated mRNA translation in cognitive impairments associated with Alzheimer's disease (AD). Accumulating evidence...
2.
Kasica N, Zhou X, Yang Q, Wang X, Yang W, Zimmermann H, et al.
J Neurochem
. 2021 Dec;
160(5):524-539.
PMID: 34932218
It is imperative to develop novel therapeutic strategies for Alzheimer's disease (AD) and related dementia syndromes based on solid mechanistic studies. Maintenance of memory and synaptic plasticity relies on de...
3.
Oliveira M, Lourenco M, Longo F, Kasica N, Yang W, Ureta G, et al.
Sci Signal
. 2021 Feb;
14(668).
PMID: 33531382
Neuronal protein synthesis is essential for long-term memory consolidation, and its dysregulation is implicated in various neurodegenerative disorders, including Alzheimer's disease (AD). Cellular stress triggers the activation of protein kinases...
4.
Zimmermann H, Yang W, Kasica N, Zhou X, Wang X, Beckelman B, et al.
J Clin Invest
. 2020 Mar;
130(7):3511-3527.
PMID: 32213711
AMPK is a key regulator at the molecular level for maintaining energy metabolism homeostasis. Mammalian AMPK is a heterotrimeric complex, and its catalytic α subunit exists in 2 isoforms: AMPKα1...
5.
Beckelman B, Yang W, Kasica N, Zimmermann H, Zhou X, Keene C, et al.
J Clin Invest
. 2019 Jan;
129(2):820-833.
PMID: 30667373
Molecular signaling mechanisms underlying Alzheimer's disease (AD) remain unclear. Maintenance of memory and synaptic plasticity depend on de novo protein synthesis, dysregulation of which is implicated in AD. Recent studies...
6.
Zimmermann H, Yang W, Beckelman B, Kasica N, Zhou X, Galli L, et al.
J Neurochem
. 2018 Jan;
146(2):133-144.
PMID: 29337352
Characterization of the molecular signaling pathways underlying protein synthesis-dependent forms of synaptic plasticity, such as late long-term potentiation (L-LTP), can provide insights not only into memory expression/maintenance under physiological conditions...