Nicolas Wieder
Overview
Explore the profile of Nicolas Wieder including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
274
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Recent Articles
11.
Wieder N, Fink R, von Wegner F
Biophys J
. 2015 Feb;
108(3):557-67.
PMID: 25650923
In this study, we numerically analyzed the nonlinear Ca(2+)-dependent gating dynamics of a single, nonconducting inositol 1,4,5-trisphosphate receptor (IP₃R) channel, using an exact and fully stochastic simulation algorithm that includes...
12.
von Wegner F, Wieder N, H A Fink R
Front Genet
. 2014 Nov;
5:376.
PMID: 25404938
Calcium ions play a key role in subcellular signaling as localized transients of the intracellular calcium concentration modify the activity of ion channels, enzymes and transcription factors, among others. The...
13.
Yeo L, Wieder N, Wang A, Ting E, Rathakrishnan R, Soon D
Neurology
. 2014 Oct;
83(15):e141-4.
PMID: 25288701
No abstract available.
14.
von Wegner F, Wieder N, H A Fink R
Adv Exp Med Biol
. 2012 Mar;
740:553-67.
PMID: 22453960
In this article, we present an overview of simulation strategies in the context of subcellular domains where calcium-dependent signaling plays an important role. The presentation follows the spatial and temporal...
15.
Wieder N, H A Fink R, von Wegner F
J Biomed Biotechnol
. 2011 Dec;
2011:572492.
PMID: 22131814
In simulations of chemical systems, the main task is to find an exact or approximate solution of the chemical master equation (CME) that satisfies certain constraints with respect to computation...