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Nicolas Denervaud

Explore the profile of Nicolas Denervaud including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 432
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Recent Articles
1.
Knight B, Kubik S, Ghosh B, Bruzzone M, Geertz M, Martin V, et al.
Genes Dev . 2014 Aug; 28(15):1695-709. PMID: 25085421
In yeast, ribosome production is controlled transcriptionally by tight coregulation of the 138 ribosomal protein genes (RPGs). RPG promoters display limited sequence homology, and the molecular basis for their coregulation...
2.
Denervaud N, Becker J, Delgado-Gonzalo R, Damay P, Rajkumar A, Unser M, et al.
Proc Natl Acad Sci U S A . 2013 Sep; 110(39):15842-7. PMID: 24019481
Observing cellular responses to perturbations is central to generating and testing hypotheses in biology. We developed a massively parallel microchemostat array capable of growing and observing 1,152 yeast-GFP strains on...
3.
Rajkumar A, Denervaud N, Maerkl S
Nat Genet . 2013 Aug; 45(10):1207-15. PMID: 23955598
The precise tuning of gene expression levels is essential for the optimal performance of transcriptional regulatory networks. We created 209 variants of the Saccharomyces cerevisiae PHO5 promoter to quantify how...
4.
Groner A, Meylan S, Ciuffi A, Zangger N, Ambrosini G, Denervaud N, et al.
PLoS Genet . 2010 Mar; 6(3):e1000869. PMID: 20221260
Krüppel-associated box domain-zinc finger proteins (KRAB-ZFPs) are tetrapod-specific transcriptional repressors encoded in the hundreds by the human genome. In order to explore their as yet ill-defined impact on gene expression,...
5.
Tigges M, Denervaud N, Greber D, Stelling J, Fussenegger M
Nucleic Acids Res . 2010 Mar; 38(8):2702-11. PMID: 20197318
Circadian clocks have long been known to be essential for the maintenance of physiological and behavioral processes in a variety of organisms ranging from plants to humans. Dysfunctions that subvert...
6.
Weber W, Schuetz M, Denervaud N, Fussenegger M
Mol Biosyst . 2009 Jun; 5(7):757-63. PMID: 19562115
Functionally well-characterized modular transcription units represent the genetic repertoire for the design of synthetic gene networks operating inside individual mammalian cells. Interconnection of specialized cells to multicellular assemblies that could...