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Nicolas Bisson

Explore the profile of Nicolas Bisson including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 490
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Recent Articles
11.
Kaplan A, Andrei S, van Regteren Altena A, Simas T, Banerjee S, Kato N, et al.
Cell Chem Biol . 2020 Mar; 27(6):657-667.e6. PMID: 32220335
Targeting protein-protein interactions (PPIs) is a promising approach in the development of drugs for many indications. 14-3-3 proteins are a family of phosphoprotein-binding molecules with critical functions in dozens of...
12.
Jacquet K, Banerjee S, Chartier F, Elowe S, Bisson N
Mol Cell Proteomics . 2018 Jul; 17(10):1979-1990. PMID: 30002203
Signals from cell surface receptors are often relayed via adaptor proteins. NCK1 and NCK2 are Src-Homology (SH) 2 and 3 domain adaptors that regulate processes requiring a remodeling of the...
13.
Dionne U, Chartier F, Lopez de Los Santos Y, Lavoie N, Bernard D, Banerjee S, et al.
Mol Cell . 2018 Jun; 70(6):995-1007.e11. PMID: 29910111
Phosphotyrosine (pTyr) signaling has evolved into a key cell-to-cell communication system. Activated receptor tyrosine kinases (RTKs) initiate several pTyr-dependent signaling networks by creating the docking sites required for the assembly...
14.
Aoidi R, Houde N, Landry-Truchon K, Holter M, Jacquet K, Charron L, et al.
Dis Model Mech . 2018 Mar; 11(3). PMID: 29590634
The RAS/MAPK signaling pathway is one of the most investigated pathways, owing to its established role in numerous cellular processes and implication in cancer. Germline mutations in genes encoding members...
15.
Banerjee S, Dionne U, Lambert J, Bisson N
J Proteomics . 2018 Feb; 189:39-47. PMID: 29425736
Protein phosphorylation often regulates interactions between components of signalling networks. Its tight regulation by opposing actions of kinases and phosphatases contribute to making this modification key in controlling the dynamic...
16.
Beigbeder A, Chartier F, Bisson N
Sci Rep . 2017 Sep; 7(1):11514. PMID: 28912526
HER2/ErbB2 is overexpressed in a significant fraction of breast tumours and is associated with a poor prognosis. The adaptor protein GRB2 interacts directly with activated HER2 and is sufficient to...
17.
Kaplan A, Morquette B, Kroner A, Leong S, Madwar C, Sanz R, et al.
Neuron . 2017 Mar; 93(5):1082-1093.e5. PMID: 28279353
Damaged central nervous system (CNS) neurons have a poor ability to spontaneously regenerate, causing persistent functional deficits after injury. Therapies that stimulate axon growth are needed to repair CNS damage....
18.
Wills M, Keyvani Chahi A, Lau H, Tilak M, Guild B, New L, et al.
J Biol Chem . 2017 Feb; 292(14):5748-5759. PMID: 28213521
Proteins of the Src homology and collagen (Shc) family are typically involved in signal transduction events involving Ras/MAPK and PI3K/Akt pathways. In the nervous system, they function proximal to the...
19.
Beigbeder A, Velot L, James D, Bisson N
Methods Mol Biol . 2016 Sep; 1458:339-47. PMID: 27581032
A precisely controlled network of protein-protein interactions constitutes the basis for functional signaling pathways. This equilibrium is more often than not disrupted in cancer cells, by the aberrant expression or...
20.
Filteau M, Diss G, Torres-Quiroz F, Dube A, Schraffl A, Bachmann V, et al.
Proc Natl Acad Sci U S A . 2015 Apr; 112(14):4501-6. PMID: 25831502
Cellular processes and homeostasis control in eukaryotic cells is achieved by the action of regulatory proteins such as protein kinase A (PKA). Although the outbound signals from PKA directed to...