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Nicolai Stuhr-Hansen

Explore the profile of Nicolai Stuhr-Hansen including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 314
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Recent Articles
1.
Stuhr-Hansen N, Vagianou C, Blixt O
Bioconjug Chem . 2019 Jul; 30(8):2156-2164. PMID: 31322865
Access to clusters of cell-sized globular objects such as giant unilamellar vesicles (GUVs) is of increasing interest due to their potential applications in prototissue and cell-cell adhesion studies. Aggregations of...
2.
Vagianou C, Stuhr-Hansen N, Moll K, Bovin N, Wahlgren M, Blixt O
ACS Chem Biol . 2018 Aug; 13(9):2421-2426. PMID: 30080386
Severe malaria is considered to be the deadliest disease of this century, primarily among children in sub-Saharan Africa. It stems from infection by the virulent parasite Plasmodium falciparum. The pathogenesis...
3.
Stuhr-Hansen N, Risinger C, Engholm E, Blixt O
Org Lett . 2017 Dec; 19(24):6522-6525. PMID: 29205042
Copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click synthesis of an Fmoc-(trispropargyl)amino acid building block for solid phase peptide synthesis (SPPS) of oligo-(trialkyne)peptide constructs is reported. These can carry potentially indefinite numbers of...
4.
Stuhr-Hansen N, Vagianou C, Blixt O
Chemistry . 2017 May; 23(40):9472-9476. PMID: 28513898
The glycocalyx cover membrane surfaces of all living cells. These complex architectures render their interaction mechanisms on the membrane surface difficult to study. Artificial cell-sized membranes with selected and defined...
5.
Persson N, Stuhr-Hansen N, Risinger C, Mereiter S, Polonia A, Polom K, et al.
Glycobiology . 2017 Apr; 27(7):635-645. PMID: 28419225
Here, we introduce a novel scFv antibody, G2-D11, specific for two adjacent Tn-antigens (GalNAc-Ser/Thr) binding equally to three dimeric forms of the epitope, Ser-Thr, Thr-Thr and Thr-Ser. Compared to other...
6.
Persson N, Jansson B, Stuhr-Hansen N, Kovacs A, Welinder C, Danielsson L, et al.
PLoS One . 2016 Dec; 11(12):e0168761. PMID: 28002485
We have developed a combinatory antibody-antigen microarray for direct screening of multiple single-chain fragment variable (scFv) clones with no need for pre-purification or enrichment before screening. The straightforward workflow allows...
7.
Andersen J, Ladefoged L, Kristensen T, Munro L, Grouleff J, Stuhr-Hansen N, et al.
ACS Chem Neurosci . 2016 Jul; 7(10):1406-1417. PMID: 27425420
The transporters for the neurotransmitters serotonin and dopamine (SERT and DAT, respectively) are targets for drugs used in the treatment of mental disorders and widely used drugs of abuse. Studies...
8.
Stuhr-Hansen N, Madl J, Villringer S, Aili U, Romer W, Blixt O
Chembiochem . 2016 May; 17(15):1403-6. PMID: 27168414
Synthetic minimal membrane systems are extremely useful for better understanding of complex cellular structures and cell surface processes. We have developed a facile method for synthesis of cholesterylated peptides, each...
9.
Kleberg K, Nielsen L, Stuhr-Hansen N, Nielsen J, Hansen H
Biofactors . 2014 Nov; 40(6):596-602. PMID: 25359532
2-Monoacylglycerols are gaining increasing interest as signaling lipids, beyond endocannabinoids, for example, as ligands for the receptor GPR119 and as mediators of insulin secretion. In the vascular system, they are...
10.
Stuhr-Hansen N, Bork N, Stromgaard K
Org Biomol Chem . 2014 Jun; 12(30):5745-51. PMID: 24967660
The influence of arylthiols on cysteine-free ligation, i.e. the reaction between an alkyl thioester and a primary amine forming an amide bond, was studied in a polar aprotic solvent. We...