Nicholas W Knoblauch
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Explore the profile of Nicholas W Knoblauch including associated specialties, affiliations and a list of published articles.
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10
Citations
480
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Recent Articles
1.
Lindstrom S, Thompson D, Paterson A, Li J, Gierach G, Scott C, et al.
Nat Commun
. 2015 Sep;
6:8358.
PMID: 26349435
No abstract available.
2.
Montaser-Kouhsari L, Knoblauch N, Oh E, Baker G, Christensen S, Hazra A, et al.
Appl Immunohistochem Mol Morphol
. 2015 Jul;
24(6):431-5.
PMID: 26186251
Sampling of formalin-fixed paraffin-embedded (FFPE) tissue blocks is a critical initial step in molecular pathology. Image-guided coring (IGC) is a new method for using digital pathology images to guide tissue...
3.
Oh E, Christensen S, Ghanta S, Jeong J, Bucur O, Glass B, et al.
Genome Biol
. 2015 Jun;
16:128.
PMID: 26087699
Background: Epithelial-stromal crosstalk plays a critical role in invasive breast cancer pathogenesis; however, little is known on a systems level about how epithelial-stromal interactions evolve during carcinogenesis. Results: We develop...
4.
Dong F, Irshad H, Oh E, Lerwill M, Brachtel E, Jones N, et al.
PLoS One
. 2014 Dec;
9(12):e114885.
PMID: 25490766
The categorization of intraductal proliferative lesions of the breast based on routine light microscopic examination of histopathologic sections is in many cases challenging, even for experienced pathologists. The development of...
5.
Lindstrom S, Thompson D, Paterson A, Li J, Gierach G, Scott C, et al.
Nat Commun
. 2014 Oct;
5:5303.
PMID: 25342443
Mammographic density reflects the amount of stromal and epithelial tissues in relation to adipose tissue in the breast and is a strong risk factor for breast cancer. Here we report...
6.
The adherens junction protein afadin is an AKT substrate that regulates breast cancer cell migration
Elloul S, Kedrin D, Knoblauch N, Beck A, Toker A
Mol Cancer Res
. 2013 Nov;
12(3):464-76.
PMID: 24269953
Unlabelled: The PI3K-AKT signaling pathway regulates all phenotypes that contribute to progression of human cancers, including breast cancer. AKT mediates signal relay by phosphorylating numerous substrates, which are causally implicated...
7.
Hefti M, Hu R, Knoblauch N, Collins L, Haibe-Kains B, Tamimi R, et al.
Breast Cancer Res
. 2013 Aug;
15(4):R68.
PMID: 23971947
Introduction: Estrogen receptor (ER) and progesterone receptor (PR) testing are performed in the evaluation of breast cancer. While the clinical utility of ER as a predictive biomarker to identify patients...
8.
French J, Ghoussaini M, Edwards S, Meyer K, Michailidou K, Ahmed S, et al.
Am J Hum Genet
. 2013 Apr;
92(4):489-503.
PMID: 23540573
Analysis of 4,405 variants in 89,050 European subjects from 41 case-control studies identified three independent association signals for estrogen-receptor-positive tumors at 11q13. The strongest signal maps to a transcriptional enhancer...
9.
Beck A, Knoblauch N, Hefti M, Kaplan J, Schnitt S, Culhane A, et al.
PLoS Comput Biol
. 2013 Feb;
9(1):e1002875.
PMID: 23365551
A major goal in translational cancer research is to identify biological signatures driving cancer progression and metastasis. A common technique applied in genomics research is to cluster patients using gene...
10.
Trainor B, Pride M, Landeros R, Knoblauch N, Takahashi E, Silva A, et al.
PLoS One
. 2011 Mar;
6(2):e17405.
PMID: 21364768
Stressful life experiences are known to be a precipitating factor for many mental disorders. The social defeat model induces behavioral responses in rodents (e.g. reduced social interaction) that are similar...