Nicholas Rachmaninoff
Overview
Explore the profile of Nicholas Rachmaninoff including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
163
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Recent Articles
1.
Apps R, Biancotto A, Candia J, Kotliarov Y, Perl S, Cheung F, et al.
Cell Rep
. 2024 Sep;
43(9):114706.
PMID: 39235945
To gain insight into how an adjuvant impacts vaccination responses, we use systems immunology to study human H5N1 influenza vaccination with or without the adjuvant AS03, longitudinally assessing 14 time...
2.
Sparks R, Rachmaninoff N, Lau W, Hirsch D, Bansal N, Martins A, et al.
Nat Med
. 2024 Jul;
30(9):2461-2472.
PMID: 38961223
Immunological health has been challenging to characterize but could be defined as the absence of immune pathology. While shared features of some immune diseases and the concept of immunologic resilience...
3.
Pranzatelli T, Perez P, Ku A, Matuck B, Huynh K, Sakai S, et al.
Res Sq
. 2024 Jan;
PMID: 38196575
Sjögren's Disease (SjD) is a systemic autoimmune disease without a clear etiology or effective therapy. Utilizing unbiased single-cell and spatial transcriptomics to analyze human minor salivary glands in health and...
4.
Sparks R, Rachmaninoff N, Hirsch D, Bansal N, Lau W, Martins A, et al.
Res Sq
. 2023 Mar;
PMID: 36993430
Monogenic diseases are often studied in isolation due to their rarity. Here we utilize multiomics to assess 22 monogenic immune-mediated conditions with age- and sex-matched healthy controls. Despite clearly detectable...
5.
Cheung F, Apps R, Dropulic L, Kotliarov Y, Chen J, Jordan T, et al.
Elife
. 2023 Jan;
12.
PMID: 36648132
Background: Both sex and prior exposure to pathogens are known to influence responses to immune challenges, but their combined effects are not well established in humans, particularly in early innate...
6.
Kardava L, Rachmaninoff N, Lau W, Buckner C, Trihemasava K, Blazkova J, et al.
Proc Natl Acad Sci U S A
. 2022 Jun;
119(28):e2204607119.
PMID: 35759653
Messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are highly effective at inducing protective immunity. However, weak antibody responses are seen in some individuals, and cellular...
7.
Kardava L, Rachmaninoff N, Lau W, Buckner C, Trihemasava K, de Assis F, et al.
medRxiv
. 2021 Jul;
PMID: 34268520
SARS-CoV-2 mRNA vaccines are highly effective, although weak antibody responses are seen in some individuals with correlates of immunity that remain poorly understood. Here we longitudinally dissected antibody, plasmablast, and...
8.
Liu C, Martins A, Lau W, Rachmaninoff N, Chen J, Imberti L, et al.
Cell
. 2021 Mar;
184(7):1836-1857.e22.
PMID: 33713619
COVID-19 exhibits extensive patient-to-patient heterogeneity. To link immune response variation to disease severity and outcome over time, we longitudinally assessed circulating proteins as well as 188 surface protein markers, transcriptome,...
9.
Bolin K, Rachmaninoff N, Moncada K, Pula K, Kennell J, Buttitta L
Dev Biol
. 2016 Feb;
412(1):83-98.
PMID: 26902111
The miR-200 microRNA family plays important tumor suppressive roles. The sole Drosophila miR-200 ortholog, miR-8 plays conserved roles in Wingless, Notch and Insulin signaling - pathways linked to tumorigenesis, yet...