Angelique Biancotto
Overview
Explore the profile of Angelique Biancotto including associated specialties, affiliations and a list of published articles.
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85
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4520
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Recent Articles
1.
Apps R, Biancotto A, Candia J, Kotliarov Y, Perl S, Cheung F, et al.
Cell Rep
. 2024 Sep;
43(9):114706.
PMID: 39235945
To gain insight into how an adjuvant impacts vaccination responses, we use systems immunology to study human H5N1 influenza vaccination with or without the adjuvant AS03, longitudinally assessing 14 time...
2.
Sparks R, Rachmaninoff N, Lau W, Hirsch D, Bansal N, Martins A, et al.
Nat Med
. 2024 Jul;
30(9):2461-2472.
PMID: 38961223
Immunological health has been challenging to characterize but could be defined as the absence of immune pathology. While shared features of some immune diseases and the concept of immunologic resilience...
3.
Sparks R, Rachmaninoff N, Hirsch D, Bansal N, Lau W, Martins A, et al.
Res Sq
. 2023 Mar;
PMID: 36993430
Monogenic diseases are often studied in isolation due to their rarity. Here we utilize multiomics to assess 22 monogenic immune-mediated conditions with age- and sex-matched healthy controls. Despite clearly detectable...
4.
de Jesus A, Chen G, Yang D, Brdicka T, Ruth N, Bennin D, et al.
Nat Commun
. 2023 Mar;
14(1):1502.
PMID: 36932076
Neutrophilic inflammation is a hallmark of many monogenic autoinflammatory diseases; pathomechanisms that regulate extravasation of damaging immune cells into surrounding tissues are poorly understood. Here we identified three unrelated boys...
5.
Cheung F, Apps R, Dropulic L, Kotliarov Y, Chen J, Jordan T, et al.
Elife
. 2023 Jan;
12.
PMID: 36648132
Background: Both sex and prior exposure to pathogens are known to influence responses to immune challenges, but their combined effects are not well established in humans, particularly in early innate...
6.
Patel T, Levine J, Elizondo D, Arner B, Jain A, Saxena A, et al.
Obesity (Silver Spring)
. 2023 Jan;
31(2):466-478.
PMID: 36628649
Objective: Colchicine is known to reduce inflammation and improve endothelial cell function and atherosclerosis in obesity, but there is little knowledge of the specific circulating leukocyte populations that are modulated...
7.
Levine J, Sarrafan-Chaharsoughi Z, Patel T, Brady S, Chivukula K, Miller E, et al.
Obesity (Silver Spring)
. 2022 Jan;
30(2):358-368.
PMID: 34978374
Objective: The aim of this study was to examine whether colchicine's anti-inflammatory effects would improve measures of lipolysis and distribution of leukocyte populations in subcutaneous adipose tissue (SAT). Methods: A...
8.
Bhat D, Olkhanud P, Gangaplara A, Seifuddin F, Pirooznia M, Biancotto A, et al.
Front Immunol
. 2021 Dec;
12:757279.
PMID: 34917079
Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is a widely available curative option for patients with sickle cell disease (SCD). Our original non-myeloablative haplo-HSCT trial employing post-transplant (PT) cyclophosphamide had a...
9.
Hasni S, Gupta S, Davis M, Poncio E, Temesgen-Oyelakin Y, Carlucci P, et al.
Nat Commun
. 2021 Jun;
12(1):3391.
PMID: 34099646
Increased risk of premature cardiovascular disease (CVD) is well recognized in systemic lupus erythematosus (SLE). Aberrant type I-Interferon (IFN)-neutrophil interactions contribute to this enhanced CVD risk. In lupus animal models,...
10.
Han K, Singh K, Rodman M, Hassanzadeh S, Wu K, Nguyen A, et al.
Nat Metab
. 2021 Mar;
3(3):318-326.
PMID: 33723462
Intermittent fasting blunts inflammation in asthma and rheumatoid arthritis, suggesting that fasting may be exploited as an immune-modulatory intervention. However, the mechanisms underpinning the anti-inflammatory effects of fasting are poorly...