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Nicholas M Murphy

Explore the profile of Nicholas M Murphy including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 72
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Recent Articles
1.
Dite G, Spaeth E, Wong C, Murphy N, Allman R
Gastro Hep Adv . 2024 Aug; 2(7):979-989. PMID: 39130772
Background And Aims: Pancreatic cancer has the poorest 5-year survival rate of any major solid tumor, but when diagnosed at an early stage, survival rates improve. Population screening is impractical...
2.
Wong C, Dite G, Spaeth E, Murphy N, Allman R
Melanoma Res . 2023 Apr; 33(4):293-299. PMID: 37096571
Melanoma is one of the most commonly diagnosed cancers in the Western world: third in Australia, fifth in the USA and sixth in the European Union. Predicting an individual's personal...
3.
Dite G, Spaeth E, Murphy N, Allman R
Prostate . 2023 Apr; 83(10):962-969. PMID: 37062910
Background: Accurate prostate cancer risk assessment will enable identification of men who are at increased risk of the disease. Using the UK Biobank population-based cohort, we developed and validated a...
4.
Dite G, Spaeth E, Murphy N, Allman R
Eur J Cancer Prev . 2022 Dec; 32(1):57-64. PMID: 36503897
Objective: Women with a family history of ovarian cancer or a pathogenic or likely pathogenic gene variant are at high risk of the disease, but very few women have these...
5.
Wong C, Makalic E, Dite G, Whiting L, Murphy N, Hopper J, et al.
PLoS One . 2022 Dec; 17(12):e0278764. PMID: 36459520
Polygenic risk scores (PRSs) are a promising approach to accurately predict an individual's risk of developing disease. The area under the receiver operating characteristic curve (AUC) of PRSs in their...
6.
Dite G, Murphy N, Spaeth E, Allman R
Epidemiol Infect . 2022 Apr; :1-15. PMID: 35465870
No abstract available.
7.
Dite G, Murphy N, Allman R
Epidemiol Infect . 2021 Jul; 149:e162. PMID: 34210368
Clinical and genetic risk factors for severe coronavirus disease 2019 (COVID-19) are often considered independently and without knowledge of the magnitudes of their effects on risk. Using severe acute respiratory...
8.
Dite G, Murphy N, Allman R
PLoS One . 2021 Feb; 16(2):e0247205. PMID: 33592063
Up to 30% of people who test positive to SARS-CoV-2 will develop severe COVID-19 and require hospitalisation. Age, gender, and comorbidities are known to be risk factors for severe COVID-19...
9.
Murphy N, Samarasekera T, Macaskill L, Mullen J, Rombauts L
Sci Rep . 2020 Mar; 10(1):3795. PMID: 32123222
Whole-genome sequencing of preimplantation human embryos to detect and screen for genetic diseases is a technically challenging extension to preconception screening. Combining preconception genetic screening with preimplantation testing of human...
10.
Masson J, Cherry C, Murphy N, Sada-Ovalle I, Hussain T, Palchaudhuri R, et al.
Front Immunol . 2018 Jun; 9:900. PMID: 29867928
Untreated HIV infection is associated with progressive CD4+ T cell depletion, which is generally recovered with combination antiretroviral therapy (cART). However, a significant proportion of cART-treated individuals have poor CD4+...