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Nicholas M Murphy

Explore the profile of Nicholas M Murphy including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 72
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11.
Murphy N, Pouton C, Irving H
Methods Mol Biol . 2017 Feb; 1551:73-85. PMID: 28138841
Here, we describe how peptide nucleic acid (PNA) probes can be used to enrich genomic DNA fractions to facilitate downstream analysis, such as the haplotype phasing of the isolated genomic...
12.
Murphy N, Burton M, Powell D, Rossello F, Cooper D, Chopra A, et al.
Sci Rep . 2016 Jul; 6:30381. PMID: 27461731
We describe a method for determining the parental HLA haplotypes of a single individual without recourse to conventional segregation genetics. Blood samples were cultured to identify and sort chromosome 6...
13.
Murphy N, Pouton C, Irving H
Mol Genet Genomic Med . 2014 Jun; 2(3):245-53. PMID: 24936514
Targeted capture of large fragments of genomic DNA that enrich for human leukocyte antigen (HLA) system haplotypes has utility in haematopoietic stem cell transplantation. Current methods of HLA matching are...
14.
Murphy N, Diviney M, Szer J, Bardy P, Grigg A, Hoyt R, et al.
Biol Blood Marrow Transplant . 2011 Sep; 18(5):722-30. PMID: 21920473
This study examined the contribution single nucleotide polymorphisms (SNPs) of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene have on clinical outcomes in hematopoietic stem cell transplant patients treated with the antiproliferative drug...