Nestor M Diaz Deleon
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Explore the profile of Nestor M Diaz Deleon including associated specialties, affiliations and a list of published articles.
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14
Citations
166
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Recent Articles
1.
Talbott H, Griffin M, Mascharak S, Parker J, Kuhnert M, Guo J, et al.
Res Sq
. 2024 Mar;
PMID: 38464040
Skin fibrosis is a clinical problem with devastating impacts but limited treatment options. In the setting of diabetes, insulin administration often causes local dermal fibrosis, leading to a range of...
2.
Griffin M, Talbott H, Guardino N, Guo J, Spielman A, Chen K, et al.
bioRxiv
. 2023 Apr;
PMID: 37066136
While past studies have suggested that plasticity exists between dermal fibroblasts and adipocytes, it remains unknown whether fat actively contributes to fibrosis in scarring. We show that adipocytes convert to...
3.
Chen K, Henn D, Januszyk M, Barrera J, Noishiki C, Bonham C, et al.
Sci Transl Med
. 2022 May;
14(645):eabj9152.
PMID: 35584231
Burns and other traumatic injuries represent a substantial biomedical burden. The current standard of care for deep injuries is autologous split-thickness skin grafting (STSG), which frequently results in contractures, abnormal...
4.
Lavin C, Abbas D, Fahy E, Lee D, Griffin M, Diaz Deleon N, et al.
J Cell Mol Med
. 2021 Oct;
25(21):10028-10038.
PMID: 34612609
The iron chelator, deferoxamine (DFO), has been shown to potentially improve dermal radiation-induced fibrosis (RIF) in mice through increased angiogenesis and reduced oxidative damage. This preclinical study evaluated the efficacy...
5.
Diaz Deleon N, Adem S, Lavin C, Abbas D, Griffin M, King M, et al.
J Tissue Eng Regen Med
. 2021 Sep;
15(12):1105-1117.
PMID: 34582109
Radiation therapy is effective for cancer treatment but may also result in collateral soft tissue contracture, contour deformities, and non-healing wounds. Autologous fat transfer has been described to improve tissue...
6.
A Novel Xenograft Model Demonstrates Human Fibroblast Behavior During Skin Wound Repair and Fibrosis
Borrelli M, Shen A, Griffin M, Mascharak S, Adem S, Diaz Deleon N, et al.
Adv Wound Care (New Rochelle)
. 2021 Sep;
11(9):455-465.
PMID: 34521222
Xenografts of human skin in immunodeficient mice provide a means of assessing human skin physiology and its response to wounding. We describe a novel xenograft model using full-thickness human neonatal...
7.
Griffin M, Borrelli M, Garcia J, Januszyk M, King M, Lerbs T, et al.
Sci Transl Med
. 2021 Sep;
13(609):eabb3312.
PMID: 34516825
Pathologic skin scarring presents a vast economic and medical burden. Unfortunately, the molecular mechanisms underlying scar formation remain to be elucidated. We used a hypertrophic scarring (HTS) mouse model in...
8.
Griffin M, Fahy E, King M, Guardino N, Chen K, Abbas D, et al.
Adv Wound Care (New Rochelle)
. 2021 Sep;
11(10):537-547.
PMID: 34470520
Skin inevitably heals with the formation of a fibrotic scar. Patients affected by skin scarring suffer from long-term psychological and physical burdens. Since the discovery of fetal scarless skin-wound healing,...
9.
Adem S, Abbas D, Lavin C, Fahy E, Griffin M, Diaz Deleon N, et al.
Adv Wound Care (New Rochelle)
. 2021 Aug;
11(10):524-536.
PMID: 34346243
Radiation therapy is commonplace for cancer treatment but often results in fibrosis and atrophy of surrounding soft tissue. Decellularized adipose matrices (DAMs) have been reported to improve these soft tissue...
10.
Lavin C, Fahy E, Abbas D, Griffin M, Diaz Deleon N, Lee D, et al.
Cleft Palate Craniofac J
. 2021 May;
59(3):330-335.
PMID: 33960204
Objective: It is important for health care education materials to be easily understood by caretakers of children requiring craniofacial surgery. This study aimed to analyze the readability of Google search...