Michael T Longaker
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Explore the profile of Michael T Longaker including associated specialties, affiliations and a list of published articles.
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632
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21196
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Recent Articles
1.
Foster D, Guo J, Meany E, Berry C, Fallah M, Korah M, et al.
Sci Transl Med
. 2025 Mar;
17(789):eadp9957.
PMID: 40073155
Postoperative abdominal adhesions are the leading cause of bowel obstruction and a cause of chronic pain and infertility. Adhesion formation occurs after 50 to 90% of abdominal operations and has...
2.
Mascharak S, Griffin M, Talbott H, Guo J, Parker J, Morgan A, et al.
Sci Transl Med
. 2025 Feb;
17(786):eadt6387.
PMID: 39970235
Modulating mechanotransduction by inhibiting yes-associated protein (YAP) in mice yields wound regeneration without scarring. However, rodents are loose-skinned and fail to recapitulate key aspects of human wound repair. We sought...
3.
Weldon K, Longaker M, Ambrosi T
Stem Cells
. 2025 Feb;
43(3).
PMID: 39945760
In our aging society, the degeneration of the musculoskeletal system and adjacent tissues is a growing orthopedic concern. As bones age, they become more fragile, increasing the risk of fractures...
4.
Hostler A, Hahn W, Hu M, Rennert R, Fischer K, Barrera J, et al.
FASEB J
. 2024 Dec;
38(24):e70210.
PMID: 39698751
C-X-C motif chemokine ligand 12 (CXCL12; Stromal Cell-Derived Factor 1 [SDF-1]), most notably known for its role in embryogenesis and hematopoiesis, has been implicated in tumor pathophysiology and neovascularization. However,...
5.
Hirsch I, Khakpour D, Joseph J, Shinohara M, Wang R, Klueh U, et al.
J Diabetes Sci Technol
. 2024 Dec;
19322968241298005.
PMID: 39633523
Ongoing innovation in diabetes technologies has led to the development of advanced tools such as automated insulin delivery (AID) systems that adjust insulin delivery in response to current and predicted...
6.
Wang H, Korah M, Jing S, Berry C, Griffin M, Longaker M, et al.
Biomedicines
. 2024 Nov;
12(11).
PMID: 39595104
Diabetes mellitus is an increasingly prevalent chronic metabolic disorder characterized by physiologic hyperglycemia that, when left uncontrolled, can lead to significant complications in multiple organs. Diabetic wounds are common in...
7.
Mascharak S, Guo J, Griffin M, Berry C, Wan D, Longaker M
Nat Rev Bioeng
. 2024 Nov;
2(4):305-323.
PMID: 39552705
Few efficacious therapies exist for the treatment of fibrotic diseases, such as skin scarring, liver cirrhosis and pulmonary fibrosis, which is related to our limited understanding of the fundamental causes...
8.
Li D, Berry C, Wan D, Longaker M
Sci Transl Med
. 2024 Sep;
16(766):eadn7871.
PMID: 39321265
When dysregulated, skin fibrosis can lead to a multitude of pathologies. We provide a framework for understanding the wide clinical spectrum, mechanisms, and management of cutaneous fibrosis encompassing a variety...
9.
Andrew T, Koepke L, Wang Y, Lopez M, Steininger H, Struck D, et al.
Nat Commun
. 2024 Sep;
15(1):8030.
PMID: 39271692
No abstract available.
10.
Guo J, Januszyk M, Longaker M
Tissue Eng Part A
. 2024 Aug;
30(19-20):589-590.
PMID: 39162812
No abstract available.