Neil J Harrison
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Explore the profile of Neil J Harrison including associated specialties, affiliations and a list of published articles.
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15
Citations
568
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Recent Articles
1.
Harrison N, Todd I, Mumtaz K
J Mater Sci
. 2020 Feb;
52(17):10517-10525.
PMID: 32025047
This work investigates whether the unique low thermal expansion property of Invar (64Fe-36Ni) is retained after processing using the additive manufacturing process selective laser melting (SLM). Using this process, near-full-density...
2.
Gokhale P, Au-Young J, Dadi S, Keys D, Harrison N, Jones M, et al.
PLoS One
. 2015 Apr;
10(4):e0123467.
PMID: 25875838
We have used single cell transcriptome analysis to re-examine the substates of early passage, karyotypically Normal, and late passage, karyotypically Abnormal ('Culture Adapted') human embryonic stem cells characterized by differential...
3.
Barbaric I, Harrison N
Int J Dev Biol
. 2012 May;
56(4):197-206.
PMID: 22562197
The pluripotent potential of embryonic stem cells has often seen them touted as the future of regenerative medicine. The road to any therapeutic success however, must stretch back to teratocarcinoma,...
4.
Lummis S, Harrison N, Wang J, Ashby J, Millen K, Beene D, et al.
ACS Chem Neurosci
. 2012 Mar;
3(3):186-192.
PMID: 22448304
The ligand binding site of Cys-loop receptors is dominated by aromatic amino acids. In GABA(C) receptors, these are predominantly tyrosine residues, with a number of other aromatic residues located in...
5.
Harrison N
J Clin Invest
. 2012 Jan;
122(2):484-6.
PMID: 22269327
The evolutionary struggles from which mutants arise have been documented in almost every living system. In this issue of the JCI, Varela and colleagues extend this list of systems to...
6.
Olariu V, Harrison N, Coca D, Gokhale P, Baker D, Billings S, et al.
Stem Cell Res
. 2009 Oct;
4(1):50-6.
PMID: 19837641
The long-term culture of human embryonic stem (ES) cells is inevitably subject to evolution, since any mutant that arises with a growth advantage will be selectively amplified. However, the evolutionary...
7.
Sonne S, Almstrup K, Dalgaard M, Juncker A, Edsgard D, Ruban L, et al.
Cancer Res
. 2009 Jun;
69(12):5241-50.
PMID: 19491264
Testicular germ cell cancers in young adult men derive from a precursor lesion called carcinoma in situ (CIS) of the testis. CIS cells were suggested to arise from primordial germ...
8.
Harrison N, Barnes J, Jones M, Baker D, Gokhale P, Andrews P
Stem Cells
. 2009 May;
27(5):1057-65.
PMID: 19415777
Human embryonic stem cells undergo adaptive changes that can increase their growth capacity upon prolonged culture in vitro. This is frequently associated with nonrandom karyotypic changes, commonly involving amplification of...
9.
Calvanese V, Horrillo A, Hmadcha A, Suarez-Alvarez B, Fernandez A, Lara E, et al.
PLoS One
. 2008 Sep;
3(9):e3294.
PMID: 18820729
Developmental genes are silenced in embryonic stem cells by a bivalent histone-based chromatin mark. It has been proposed that this mark also confers a predisposition to aberrant DNA promoter hypermethylation...
10.
Harrison N, Baker D, Andrews P
Int J Androl
. 2007 May;
30(4):275-81.
PMID: 17488340
Teratocarcinomas are a subset of tumours that result from the neoplastic transformation of primordial germ cells. Such germ cell tumours (GCT) are histologically heterogeneous, reflecting a capacity for differentiation (pluripotency)...