Negar Makhsous
Overview
Explore the profile of Negar Makhsous including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
390
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0
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Recent Articles
1.
Makhsous N, Goya S, Avendano C, Rupp J, Kuypers J, Jerome K, et al.
J Infect Dis
. 2023 Jul;
229(2):403-412.
PMID: 37486790
Background: Rhinovirus (RV) infections can progress from the upper (URT) to lower (LRT) respiratory tract in immunocompromised individuals, causing high rates of fatal pneumonia. Little is known about how RV...
2.
Makhsous N, Goya S, Avendano C, Rupp J, Kuypers J, Jerome K, et al.
bioRxiv
. 2023 May;
PMID: 37214809
Background: Human rhinovirus (HRV) infections can progress from the upper (URT) to lower (LRT) respiratory tract in immunocompromised individuals, causing high rates of fatal pneumonia. Little is known about how...
3.
Greninger A, Rybkina K, Lin M, Drew-Bear J, Marcink T, Shean R, et al.
J Clin Invest
. 2021 Oct;
131(23).
PMID: 34609969
The capacity of respiratory viruses to undergo evolution within the respiratory tract raises the possibility of evolution under the selective pressure of the host environment or drug treatment. Long-term infections...
4.
Aubert M, Strongin D, Roychoudhury P, Loprieno M, Haick A, Klouser L, et al.
Nat Commun
. 2020 Aug;
11(1):4148.
PMID: 32811834
We evaluate gene editing of HSV in a well-established mouse model, using adeno-associated virus (AAV)-delivered meganucleases, as a potentially curative approach to treat latent HSV infection. Here we show that...
5.
Cox R, Sourimant J, Toots M, Yoon J, Ikegame S, Govindarajan M, et al.
Nat Microbiol
. 2020 Jul;
5(10):1232-1246.
PMID: 32661315
Paramyxoviruses such as human parainfluenza virus type-3 (HPIV3) and measles virus (MeV) are a substantial health threat. In a high-throughput screen for inhibitors of HPIV3 (a major cause of acute...
6.
Ikuta K, Roychoudhury P, Xie H, McClurkan C, Walkiewicz M, Makhsous N, et al.
Open Forum Infect Dis
. 2019 Nov;
6(11):ofz465.
PMID: 31777756
We describe a case of acute liver failure and myopericarditis due to herpes simplex virus-1 (HSV-1) in an immunocompetent adult. We estimate that, at the height of viremia, the patient...
7.
Toots M, Yoon J, Cox R, Hart M, Sticher Z, Makhsous N, et al.
Sci Transl Med
. 2019 Oct;
11(515).
PMID: 31645453
Influenza viruses constitute a major health threat and economic burden globally, frequently exacerbated by preexisting or rapidly emerging resistance to antiviral therapeutics. To address the unmet need of improved influenza...
8.
Starr K, Greninger A, Makhsous N, Jerome K, Cook L
J Clin Microbiol
. 2019 Aug;
57(11).
PMID: 31434723
Adenoviruses (AdV) have been associated with a variety of human diseases and are recognized as causing significant morbidity and mortality in immunocompromised or transplant patients. Quantification of AdV DNA in...
9.
Addetia A, Greninger A, Adler A, Yuan S, Makhsous N, Qin X, et al.
Antimicrob Agents Chemother
. 2019 Apr;
63(6).
PMID: 30988144
Chlorhexidine gluconate (CHG) is a topical antiseptic widely used in health care settings. In spp., the pump QacA effluxes CHG, while the closely related QacB cannot due to a single...
10.
Shean R, Makhsous N, Stoddard G, Lin M, Greninger A
BMC Bioinformatics
. 2019 Jan;
20(1):48.
PMID: 30674273
Background: With sequencing technologies becoming cheaper and easier to use, more groups are able to obtain whole genome sequences of viruses of public health and scientific importance. Submission of genomic...