Nechama I Smorodinsky
Overview
Explore the profile of Nechama I Smorodinsky including associated specialties, affiliations and a list of published articles.
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25
Citations
587
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Recent Articles
1.
Shmerling M, Chalik M, Smorodinsky N, Meeker A, Roy S, Sagi-Assif O, et al.
Immunohorizons
. 2022 Apr;
6(4):253-272.
PMID: 35440514
Syntenic genomic loci on human chromosome 8 and mouse chromosome 15 (mChr15) code for LY6/Ly6 (lymphocyte Ag 6) family proteins. The 23 murine family genes include eight genes that are...
2.
Pichinuk E, Chalik M, Benhar I, Ginat-Koton R, Ziv R, Smorodinsky N, et al.
Cancer Immunol Immunother
. 2020 Mar;
69(7):1337-1352.
PMID: 32219500
Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies (mAbs) directed against the MUC1 alpha-beta junction comprising the SEA domain,...
3.
Hirschhorn T, Levi-Hofman M, Danziger O, Smorodinsky N, Ehrlich M
Cell Mol Life Sci
. 2017 Mar;
74(14):2645-2662.
PMID: 28357470
The Type-I bone morphogenetic protein receptors (BMPRs), BMPR1A and BMPR1B, present the highest sequence homology among BMPRs, suggestive of functional similitude. However, sequence elements within their extracellular domain, such as...
4.
Oliva M, Butenko Y, Hsieh T, Hakim O, Katz A, Smorodinsky N, et al.
J Exp Bot
. 2016 Nov;
67(21):6111-6123.
PMID: 27811080
Polycomb group (PcG) proteins are evolutionarily conserved chromatin modifiers that regulate developmental pathways in plants. PcGs form nuclear multi-subunit Polycomb Repressive Complexes (PRCs). The PRC2 complex mediates gene repression via...
5.
Chalick M, Jacobi O, Pichinuk E, Garbar C, Bensussan A, Meeker A, et al.
PLoS One
. 2016 Oct;
11(10):e0165031.
PMID: 27768738
Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The MUC1 gene encodes MUC1-TM, a signal-transducing trans-membrane protein...
6.
Hirschhorn T, Clemente N, Amsalem A, Pepinsky R, Picard J, Smorodinsky N, et al.
J Cell Sci
. 2015 Feb;
128(7):1352-64.
PMID: 25663701
The levels and intracellular localization of wild-type transforming growth factor β superfamily (TGFβ-SF) receptors are tightly regulated by endocytic trafficking, shedding and degradation. In contrast, a main regulatory mechanism of...
7.
Shapira K, Hirschhorn T, Barzilay L, Smorodinsky N, Henis Y, Ehrlich M
Mol Biol Cell
. 2014 Mar;
25(10):1620-8.
PMID: 24648493
Transforming growth factor-β (TGF-β) ligands activate Smad-mediated and noncanonical signaling pathways in a cell context-dependent manner. Localization of signaling receptors to distinct membrane domains is a potential source of signaling...
8.
Kovjazin R, Horn G, Smorodinsky N, Shapira M, Carmon L
PLoS One
. 2014 Jan;
9(1):e85400.
PMID: 24416403
The MUC1 tumor associated antigen is highly expressed on a range of tumors. Its broad distribution on primary tumors and metastases renders it an attractive target for immunotherapy. After synthesis...
9.
Shai B, Schmukler E, Yaniv R, Ziv N, Horn G, Bumbarov V, et al.
J Virol
. 2013 Oct;
87(24):13397-408.
PMID: 24089565
The mode and timing of virally induced cell death hold the potential of regulating viral yield, viral transmission, and the severity of virally induced disease. Orbiviruses such as the epizootic...
10.
Kovjazin R, Shitrit D, Preiss R, Haim I, Triezer L, Fuks L, et al.
Clin Vaccine Immunol
. 2013 Jan;
20(3):328-40.
PMID: 23283639
The low protection by the bacillus Calmette-Guérin (BCG) vaccine and existence of drug-resistant strains require better anti-Mycobacterium tuberculosis vaccines with a broad, long-lasting, antigen-specific response. Using bioinformatics tools, we identified...