Nazbeh Taghizadeh
Overview
Explore the profile of Nazbeh Taghizadeh including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
25
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0
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Recent Articles
1.
Arico-Muendel C, Belanger B, Benjamin D, Blanchette H, Caiazzo T, Centrella P, et al.
Drug Metab Dispos
. 2013 Jan;
41(4):814-26.
PMID: 23355637
The natural product fumagillin exhibits potent antiproliferative and antiangiogenic properties. The semisynthetic analog PPI-2458, [(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] N-[(2R)-1-amino-3-methyl-1-oxobutan-2-yl]carbamate, demonstrates rapid inactivation of its molecular target, methionine aminopeptidase-2 (MetAP2), and good efficacy in...
2.
Evindar G, Satz A, Bernier S, Kavarana M, Doyle E, Lorusso J, et al.
Bioorg Med Chem Lett
. 2009 Mar;
19(8):2315-9.
PMID: 19282175
In pursuit of potent and selective sphingosine-1-phosphate receptor agonists, we have utilized previously reported phenylamide and phenylimidazole scaffolds to explore extensive side-chain modifications to generate new molecular entities. A number...
3.
Bernier S, Taghizadeh N, Thompson C, Westlin W, Hannig G
J Cell Biochem
. 2005 Jun;
95(6):1191-203.
PMID: 15962312
The dependence of cell growth on methionine aminopeptidase (MetAP) function in bacteria and yeast is firmly established. Here we report experimental evidence that the control of cell proliferation in mammalian...