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Nayan J Sarma

Explore the profile of Nayan J Sarma including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 433
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Recent Articles
1.
Sarma N, Tiriveedhi V, Crippin J, Chapman W, Mohanakumar T
J Virol . 2014 Jan; 88(7):3733-43. PMID: 24429361
Unlabelled: Hepatitis C virus (HCV)-mediated liver diseases are one of the major health issues in the United States and worldwide. HCV infection has been reported to modulate microRNAs (miRNAs) that...
2.
Tiriveedhi V, Upadhya G, Busch R, Gunter K, Dines J, Knolhoff B, et al.
Transpl Immunol . 2014 Jan; 30(2-3):93-8. PMID: 24380732
Steatotic liver grafts tolerate ischemia-reperfusion (I/R) injury poorly, contributing to poor survival following transplantation. However the molecular mechanisms leading to I/R injury still remain to be defined. We have previously...
3.
Ramachandran S, Basha H, Sarma N, Lin Y, Crippin J, Chapman W, et al.
PLoS One . 2013 Aug; 8(8):e70744. PMID: 23950995
Hepatitis C virus (HCV) induced liver disease is the leading indication for liver transplantation (LTx). Reinfection and accelerated development of fibrosis is a universal phenomenon following LTx. The molecular events...
4.
Angaswamy N, Tiriveedhi V, Sarma N, Subramanian V, Klein C, Wellen J, et al.
Hum Immunol . 2013 Jul; 74(11):1478-85. PMID: 23876679
Recent studies strongly suggest an increasing role for immune responses against self-antigens (Ags) which are not encoded by the major histocompatibility complex in the immunopathogenesis of allograft rejection. Although, improved...
5.
Tiriveedhi V, Gautam B, Sarma N, Askar M, Budev M, Aloush A, et al.
J Heart Lung Transplant . 2013 Jul; 32(8):807-14. PMID: 23856218
Background: Immune responses to lung-associated self-antigens (SAgs) have been implicated in chronic lung allograft rejection. The goals of this study were to determine the prevalence of pre-existing antibodies (Abs) to...
6.
Sarma N, Yaseen N
PLoS One . 2013 Jul; 8(6):e67032. PMID: 23840580
The chimeric oncoprotein NUP98-HOXA9 results from the t(7;11)(p15;p15) chromosomal translocation and is associated with acute myeloid leukemia. It causes aberrant gene regulation and leukemic transformation through mechanisms that are not...
7.
Sarma N, Tiriveedhi V, Mohanakumar T
Methods Mol Biol . 2013 Jun; 1034:335-41. PMID: 23775748
The enzyme-linked immunosorbent assay (ELISA) is a widely used technique for detecting antibodies (Abs) and is employed in clinical laboratories to identify Abs against various self-antigens-autoAb development and quantitation. This...
8.
Tiriveedhi V, Takenaka M, Sarma N, Gelman A, Mohanakumar T
J Heart Lung Transplant . 2013 May; 32(7):714-22. PMID: 23643508
Background: The goal of this study was to define the role of T-cell sub-sets in the pathogenesis of autoimmunity-induced obliterative airway disease by passive transfer of CD8+ or CD4+ T...
9.
Sarma N, Tiriveedhi V, Subramanian V, Shenoy S, Crippin J, Chapman W, et al.
PLoS One . 2012 Dec; 7(11):e50826. PMID: 23226395
Liver disease due to hepatitis C virus (HCV) infection is an important health problem worldwide. HCV induced changes in microRNAs (miRNA) are shown to mediate inflammation leading to liver fibrosis....
10.
Sarma N, Willis K
Nucleus . 2012 Oct; 3(6):508-15. PMID: 23047597
Transcriptional regulation is a complex process that requires the integrated action of many multi-protein complexes. The way in which a living cell coordinates the action of these complexes in time...