Nathaniel S Schocker
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Explore the profile of Nathaniel S Schocker including associated specialties, affiliations and a list of published articles.
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11
Citations
126
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Recent Articles
1.
Ward E, Zamora C, Schocker N, Ghosh S, Kizer M, Imperiali B
ACS Chem Biol
. 2022 Dec;
18(1):70-80.
PMID: 36525666
Glycan-binding proteins (GBPs) are widely used reagents for basic research and clinical applications. These reagents allow for the identification and manipulation of glycan determinants without specialized equipment or time-consuming experimental...
2.
Ortega-Rodriguez U, Portillo S, Ashmus R, Duran J, Schocker N, Iniguez E, et al.
Methods Mol Biol
. 2019 Mar;
1955:287-308.
PMID: 30868536
Chagas disease (ChD), caused by the protozoan parasite Trypanosoma cruzi, affects millions of people worldwide. Chemotherapy is restricted to two drugs, which are partially effective and may cause severe side...
3.
Madec A, Schocker N, Sanchini S, Myratgeldiyev G, Das D, Imperiali B
ACS Chem Biol
. 2018 Aug;
13(9):2542-2550.
PMID: 30080379
The privileged uptake of nucleosides into cells has generated interest in the development of nucleoside-analog libraries for mining new inhibitors. Of particular interest are applications in the discovery of substrate...
4.
Subramaniam K, Austin V, Schocker N, Montoya A, Anderson M, Ashmus R, et al.
Parasitology
. 2018 Jun;
145(13):1758-1764.
PMID: 29898796
Outbreaks of Old World cutaneous leishmaniasis (CL) have significantly increased due to the conflicts in the Middle East, with most of the cases occurring in resource-limited areas such as refugee...
5.
Iniguez E, Schocker N, Subramaniam K, Portillo S, Montoya A, Al-Salem W, et al.
PLoS Negl Trop Dis
. 2017 Oct;
11(10):e0006039.
PMID: 29069089
Background: Protozoan parasites from the genus Leishmania cause broad clinical manifestations known as leishmaniases, which affect millions of people worldwide. Cutaneous leishmaniasis (CL), caused by L. major, is one the...
6.
Zamora C, Schocker N, Chang M, Imperiali B
Methods Enzymol
. 2017 Sep;
597:145-186.
PMID: 28935101
This method describes the chemoenzymatic synthesis of several nucleotide sugars, which are essential substrates in the biosynthesis of prokaryotic N- and O-linked glycoproteins. Protein glycosylation is now known to be...
7.
Zheng X, Zhang X, Schocker N, Renslow R, Orton D, Khamsi J, et al.
Anal Bioanal Chem
. 2016 Sep;
409(2):467-476.
PMID: 27604268
Glycomics has become an increasingly important field of research since glycans play critical roles in biology processes ranging from molecular recognition and signaling to cellular communication. Glycans often conjugate with...
8.
Schocker N, Portillo S, Brito C, Marques A, Almeida I, Michael K
Glycobiology
. 2015 Sep;
26(1):39-50.
PMID: 26384953
The protozoan parasite, Trypanosoma cruzi, the etiologic agent of Chagas disease (ChD), has a cell surface covered by immunogenic glycoconjugates. One of the immunodominant glycotopes, the trisaccharide Galα(1,3)Galβ(1,4)GlcNAcα, is expressed...
9.
Ashmus R, Schocker N, Cordero-Mendoza Y, Marques A, Monroy E, Pardo A, et al.
Org Biomol Chem
. 2013 Jul;
11(34):5579-83.
PMID: 23863943
A synthetic glycoarray containing non-reducing α-galactopyranosyl moieties related to mucin O-glycans of the parasite Trypanosoma cruzi was evaluated by a chemiluminescent enzyme-linked immunosorbent assay with sera from patients with chronic...
10.
Song W, DeLyria E, Chen J, Huang W, Lee J, Mittendorf E, et al.
Int J Oncol
. 2012 Oct;
41(6):1977-84.
PMID: 23023583
Bioinformatic tools and databases for glycobiology and glycomics research are playing increasingly important roles in functional studies. However, to verify hypotheses generated by computational glycomics with empirical functional assays is...