Igor C Almeida
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Explore the profile of Igor C Almeida including associated specialties, affiliations and a list of published articles.
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Articles
125
Citations
4035
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Recent Articles
1.
Farani P, Lopez J, Faier-Pereira A, Hasslocher-Moreno A, Almeida I, Moreira O
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940705
Chagas disease, caused by , remains a significant global health challenge, particularly in the molecular diagnostics of low parasitemia during the chronic phase. This highlights the critical need for enhanced...
2.
Vinales I, Silva-Espinoza J, Medina B, Urbay J, Beltran M, Salinas D, et al.
ACS Omega
. 2024 Sep;
9(38):39533-39545.
PMID: 39346819
Despite considerable progress in using lipid nanoparticle (LNP) vehicles for gene delivery, achieving selective transfection of specific cell types remains a significant challenge, hindering the advancement of new gene or...
3.
Croft J, Grajeda B, Aguirre L, Abou-Fadel J, Ellis C, Estevao I, et al.
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38731959
Cerebral cavernous malformations (CCMs) are a neurological disorder characterized by enlarged intracranial capillaries in the brain, increasing the susceptibility to hemorrhagic strokes, a major cause of death and disability worldwide....
4.
Montoya A, Gil E, Vinales I, Estevao I, Taboada P, Torrico M, et al.
Carbohydr Res
. 2024 Jan;
536:109015.
PMID: 38198982
The protozoan parasite Leishmania (Viannia) braziliensis is among Latin America's most widespread Leishmania species and is responsible for tegumentary leishmaniasis (TL). This disease has multiple clinical presentations, with cutaneous leishmaniasis...
5.
Valdez A, de Souza T, Artunduaga Bonilla J, Zamith-Miranda D, Piffer A, Araujo G, et al.
J Fungi (Basel)
. 2023 Nov;
9(11).
PMID: 37998859
is the causative agent of histoplasmosis. Treating this fungal infection conventionally has significant limitations, prompting the search for alternative therapies. In this context, fungal extracellular vesicles (EVs) hold relevant potential...
6.
Zhang R, Peng X, Du J, Boohaker R, Estevao I, Grajeda B, et al.
Cancer Res
. 2023 Sep;
83(22):3739-3752.
PMID: 37695315
Significance: Upregulation of SLC25A1 induced by KRASG12D-GLI1 signaling rewires lipid metabolism and is exacerbated by HFD to drive the development of pancreatic cancer, representing a targetable metabolic axis to suppress...
7.
Pagura L, Dumoulin P, Ellis C, Mendes M, Estevao I, Almeida I, et al.
J Biol Chem
. 2023 Apr;
299(6):104715.
PMID: 37061002
Trypanosomatids are a diverse group of uniflagellate protozoan parasites that include globally relevant pathogens such as Trypanosoma cruzi, the causative agent of Chagas disease. Trypanosomes lack the fatty acid synthase...
8.
Casas-Sanchez A, Ramaswamy R, Perally S, Haines L, Rose C, Aguilera-Flores M, et al.
PLoS Pathog
. 2023 Mar;
19(3):e1011269.
PMID: 36996244
Trypanosoma brucei spp. develop into mammalian-infectious metacyclic trypomastigotes inside tsetse salivary glands. Besides acquiring a variant surface glycoprotein (VSG) coat, little is known about the metacyclic expression of invariant surface...
9.
Farani P, Iandra da Silva Ferreira B, Begum K, Vilar-Pereira G, Resende Pereira I, Fernandez-Figueroa E, et al.
PLoS Negl Trop Dis
. 2023 Mar;
17(3):e0011223.
PMID: 36972298
Chronic Chagas cardiomyopathy (CCC) is one of the leading causes of morbidity and mortality due to cardiovascular disorders in endemic areas of Chagas disease (CD), a neglected tropical illness caused...
10.
Baily P, Del Castillo H, Vinales I, Urbay J, Paez A, Weaver M, et al.
ACS Omega
. 2023 Mar;
8(10):9486-9498.
PMID: 36936343
The photolytic properties of -acyl-7-nitroindolines make these compounds attractive as photocleavable protecting groups and "caged" compounds for the light-induced release ("uncaging") of biologically active compounds and as acylating reagents under...