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Nathanael Lemonnier

Explore the profile of Nathanael Lemonnier including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 1040
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Recent Articles
1.
Montellier E, Lemonnier N, Penkert J, Freycon C, Blanchet S, Amadou A, et al.
iScience . 2024 Dec; 27(12):111296. PMID: 39634561
Li-Fraumeni syndrome (LFS) is a heterogeneous predisposition to an individually variable spectrum of cancers caused by pathogenic germline variants. We used a clustering method to assign TP53 missense variants to...
2.
Aguilar D, Lemonnier N, Melen E, Bustamante M, Gruzieva O, Guerra S, et al.
Sci Rep . 2023 Aug; 13(1):13125. PMID: 37573373
The concept of "one-airway-one-disease", coined over 20 years ago, may be an over-simplification of the links between allergic diseases. Genomic studies suggest that rhinitis alone and rhinitis with asthma are...
3.
Guerra S, Ledford J, Melen E, Lavi I, Carsin A, Stern D, et al.
Am J Respir Crit Care Med . 2022 Jul; 207(5):544-552. PMID: 35876143
The identification of novel molecules associated with asthma may provide insights into the mechanisms of disease and their potential clinical implications. To conduct a screening of circulating proteins in childhood...
4.
Merid S, Bustamante M, Standl M, Sunyer J, Heinrich J, Lemonnier N, et al.
Environ Int . 2020 Nov; 146:106248. PMID: 33212358
Air pollution has been associated with adverse health effects across the life-course. Although underlying mechanisms are unclear, several studies suggested pollutant-induced changes in transcriptomic profiles. In this meta-analysis of transcriptome-wide...
5.
Lemonnier N, Melen E, Jiang Y, Joly S, Menard C, Aguilar D, et al.
Allergy . 2020 Apr; 75(12):3248-3260. PMID: 32277847
Background: Allergic diseases often occur in combination (multimorbidity). Human blood transcriptome studies have not addressed multimorbidity. Large-scale gene expression data were combined to retrieve biomarkers and signaling pathways to disentangle...
6.
Aguilar D, Lemonnier N, Koppelman G, Melen E, Oliva B, Pinart M, et al.
PLoS One . 2019 Nov; 14(11):e0224448. PMID: 31693680
Background: The mechanisms explaining multimorbidity between asthma, dermatitis and rhinitis (allergic multimorbidity) are not well known. We investigated these mechanisms and their specificity in distinct cell types by means of...
7.
Gruzieva O, Xu C, Yousefi P, Relton C, Merid S, Breton C, et al.
Environ Health Perspect . 2019 Jun; 127(5):57012. PMID: 31148503
Background: Prenatal exposure to air pollution has been associated with childhood respiratory disease and other adverse outcomes. Epigenetics is a suggested link between exposures and health outcomes. Objectives: We aimed...
8.
de Andrade K, Frone M, Wegman-Ostrosky T, Khincha P, Kim J, Amadou A, et al.
Hum Mutat . 2019 Apr; 40(6):832-833. PMID: 30997946
No abstract available.
9.
de Andrade K, Frone M, Wegman-Ostrosky T, Khincha P, Kim J, Amadou A, et al.
Hum Mutat . 2018 Oct; 40(1):97-105. PMID: 30352134
Reports of variable cancer penetrance in Li-Fraumeni syndrome (LFS) have raised questions regarding the prevalence of pathogenic germline TP53 variants. We previously reported higher-than-expected population prevalence estimates in sequencing databases...
10.
Mazein A, Ostaszewski M, Kuperstein I, Watterson S, Le Novere N, Lefaudeux D, et al.
NPJ Syst Biol Appl . 2018 Jun; 4:21. PMID: 29872544
The development of computational approaches in systems biology has reached a state of maturity that allows their transition to systems medicine. Despite this progress, intuitive visualisation and context-dependent knowledge representation...