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Charles Auffray

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Articles 139
Citations 4483
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Recent Articles
1.
Kermani N, Chung K, Macis G, Santini G, Clemeno F, Versi A, et al.
Eur Respir J . 2024 Oct; 64(5). PMID: 39401856
Background: Lung quantitative computed tomography (qCT) severe asthma clusters have been reported, but their replication and underlying disease mechanisms are unknown. We identified and replicated qCT clusters of severe asthma...
2.
Niarakis A, Ostaszewski M, Mazein A, Kuperstein I, Kutmon M, Gillespie M, et al.
Front Immunol . 2024 Feb; 14:1282859. PMID: 38414974
Introduction: The COVID-19 Disease Map project is a large-scale community effort uniting 277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic content describing SARS-CoV-2-host interactions and develop...
3.
I Abdel-Aziz M, Thorsen J, Hashimoto S, Vijverberg S, Neerincx A, Brinkman P, et al.
Am J Respir Crit Care Med . 2023 May; 208(2):142-154. PMID: 37163754
Children with preschool wheezing or school-age asthma are reported to have airway microbial imbalances. To identify clusters in children with asthma or wheezing using oropharyngeal microbiota profiles. Oropharyngeal swabs from...
4.
Hou R, Ye G, Cheng X, Shaw D, Bakke P, Caruso M, et al.
Brain Behav Immun . 2023 May; 111:249-258. PMID: 37146653
Background: Growing evidence indicates high comorbid anxiety and depression in patients with asthma. However, the mechanisms underlying this comorbid condition remain unclear. The aim of this study was to investigate...
5.
Pison C, Tissot A, Bernasconi E, Royer P, Roux A, Koutsokera A, et al.
Front Med (Lausanne) . 2023 Mar; 10:1126697. PMID: 36968829
Background: Chronic lung allograft dysfunction (CLAD) is the leading cause of poor long-term survival after lung transplantation (LT). Systems prediction of Chronic Lung Allograft Dysfunction (SysCLAD) aimed to predict CLAD....
6.
Balaur I, Roy L, Toure V, Mazein A, Auffray C
J Integr Bioinform . 2022 Dec; 19(4). PMID: 36563404
Systems biology researchers need feasible solutions for editing and visualisation of large biological diagrams. Here, we present the ySBGN bidirectional converter that translates metabolic pathways, developed in the general-purpose yEd...
7.
Auffray J, Auffray C
Prog Biophys Mol Biol . 2022 Sep; 175:73-78. PMID: 36126800
A characteristic of living systems is their ability to self-organize. Using appropriate quantum mechanical and mathematical tools, we show that this ability may also be a characteristic of non-living systems,...
8.
Thorsen J, Stokholm J, Rasmussen M, Roggenbuck-Wedemeyer M, Vissing N, Mortensen M, et al.
Ann Am Thorac Soc . 2022 Jul; 19(12):2031-2043. PMID: 35904980
There is a major unmet need for improving the care of children and adolescents with severe asthma and wheeze. Identifying factors contributing to disease severity may lead to improved diagnostics,...
9.
Hoda U, Pavlidis S, Bansal A, Takahashi K, Hu S, Ng Kee Kwong F, et al.
Clin Transl Med . 2022 Apr; 12(4):e816. PMID: 35474304
Background: Exacerbation-prone asthma is a feature of severe disease. However, the basis for its persistency remains unclear. Objectives: To determine the clinical and transcriptomic features of frequent exacerbators (FEs) and...
10.
Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, et al.
Mol Syst Biol . 2021 Dec; 17(12):e10851. PMID: 34939300
No abstract available.