Nathan W Bartlett
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Explore the profile of Nathan W Bartlett including associated specialties, affiliations and a list of published articles.
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73
Citations
3608
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Recent Articles
11.
Antunes K, Singanayagam A, Williams L, Faiez T, Farias A, Jackson M, et al.
J Allergy Clin Immunol
. 2022 Oct;
151(2):447-457.e5.
PMID: 36216081
Background: Microbiota are recognized to play a major role in regulation of immunity through release of immunomodulatory metabolites such as short-chain fatty acids (SCFAs). Rhinoviruses (RVs) induce upper respiratory tract...
12.
Veerati P, Nichol K, Read J, Bartlett N, Wark P, Knight D, et al.
Am J Physiol Lung Cell Mol Physiol
. 2022 Aug;
323(4):L495-L502.
PMID: 36041223
Primary bronchial epithelial cells (pBECs) obtained from donors have limited proliferation capacity. Recently, conditional reprogramming (CR) technique has overcome this and has provided the potential for extended passaging and subsequent...
13.
Aggarwal A, Stella A, Walker G, Akerman A, Esneau C, Milogiannakis V, et al.
Nat Microbiol
. 2022 May;
7(6):896-908.
PMID: 35637329
Genetically distinct variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged since the start of the COVID-19 pandemic. Over this period, we developed a rapid platform (R-20) for...
14.
Williams T, Loo S, Nichol K, Reid A, Veerati P, Esneau C, et al.
Commun Biol
. 2022 May;
5(1):415.
PMID: 35508632
IL-25 is implicated in the pathogenesis of viral asthma exacerbations. However, the effect of IL-25 on antiviral immunity has yet to be elucidated. We observed abundant expression and colocalization of...
15.
Toll-like receptor-agonist-based therapies for respiratory viral diseases: thinking outside the cell
Girkin J, Maltby S, Bartlett N
Eur Respir Rev
. 2022 May;
31(164).
PMID: 35508333
Respiratory virus infections initiate in the upper respiratory tract (URT). Innate immunity is critical for initial control of infection at this site, particularly in the absence of mucosal virus-neutralising antibodies....
16.
Singanayagam A, Footitt J, Marczynski M, Radicioni G, Cross M, Finney L, et al.
J Clin Invest
. 2022 Mar;
132(8).
PMID: 35239513
The respiratory tract surface is protected from inhaled pathogens by a secreted layer of mucus rich in mucin glycoproteins. Abnormal mucus accumulation is a cardinal feature of chronic respiratory diseases,...
17.
Esneau C, Duff A, Bartlett N
Viruses
. 2022 Jan;
14(1).
PMID: 35062345
Rhinoviruses (RVs) have been reported as one of the main viral causes for severe respiratory illnesses that may require hospitalization, competing with the burden of other respiratory viruses such as...
18.
Shimoda L, Bai C, Bartlett N, Bastarache J, Feghali-Bostwick C, J Gunst S, et al.
Am J Physiol Lung Cell Mol Physiol
. 2021 Sep;
321(5):L844-L846.
PMID: 34585617
No abstract available.
19.
Schuliga M, Kanwal A, Read J, Blokland K, Burgess J, Prele C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2021 Sep;
321(5):L859-L871.
PMID: 34524912
Alveolar epithelial cell (AEC) senescence is implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Mitochondrial dysfunction including release of mitochondrial DNA (mtDNA) is a feature of senescence, which led...
20.
Collison A, Sokulsky L, Kepreotes E, Pereira de Siqueira A, Morten M, Edwards M, et al.
JCI Insight
. 2021 Apr;
6(7).
PMID: 33830082
Virus-induced respiratory tract infections are a major health burden in childhood, and available treatments are supportive rather than disease modifying. Rhinoviruses (RVs), the cause of approximately 80% of common colds,...