Michael R Edwards
Overview
Explore the profile of Michael R Edwards including associated specialties, affiliations and a list of published articles.
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129
Citations
4887
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Recent Articles
1.
Zhu J, Edwards M, Message S, Stanciu L, Johnston S, Jeffery P
Pharmaceuticals (Basel)
. 2024 Nov;
17(11).
PMID: 39598462
Cilomilast, a phosphodiesterase-4 (PDE4) selective inhibitor, has anti-inflammatory effects in vitro and in vivo and reduces COPD exacerbations. We tested the hypothesis that cilomilast inhibits virus-induced airway epithelial intercellular adhesion...
2.
Finney L, Fenwick P, Kemp S, Singanayagam A, Edwards M, Belchamber K, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Nov;
328(1):L120-L133.
PMID: 39560620
Respiratory viruses cause chronic obstructive pulmonary disease (COPD) exacerbations. Rhinoviruses (RVs) are the most frequently detected. Some patients with COPD experience frequent exacerbations (≥2 exacerbations/yr). The relationship between exacerbation frequency...
3.
Rupani H, Chaudhuri R, Jackson D, Moyses H, Kurukulaaratchy R, Haitchi H, et al.
J Allergy Clin Immunol
. 2024 Nov;
155(1):236-237.
PMID: 39520415
No abstract available.
4.
Messaoud-Nacer Y, Culerier E, Rose S, Maillet I, Boussad R, Veront C, et al.
Allergy
. 2024 Oct;
80(3):715-737.
PMID: 39466641
Background: Severe refractory, neutrophilic asthma remains an unsolved clinical problem. STING agonists induce a neutrophilic response in the airways, suggesting that STING activation may contribute to the triggering of neutrophilic...
5.
Rupani H, Edwards D, Chaudhuri R, Smith S, Jackson D, Hearn A, et al.
J Allergy Clin Immunol Pract
. 2024 May;
12(9):2510-2513.e2.
PMID: 38796102
No abstract available.
6.
Regis E, Fontanella S, Curtin J, Pinot de Moira A, Edwards M, Murray C, et al.
J Allergy Clin Immunol
. 2024 Mar;
154(2):308-315.
PMID: 38494094
Background: Single nucleotide polymorphisms (SNPs) in genes on chromosome 17q12-q21 are associated with childhood-onset asthma and rhinovirus-induced wheeze. There are few mechanistic data linking chromosome 17q12-q21 to wheezing illness. Objective:...
7.
Gutierrez F, Murphy Q, Swartwout B, Read K, Edwards M, Abdelhamid L, et al.
Immunohorizons
. 2024 Feb;
8(2):172-181.
PMID: 38353996
Aryl hydrocarbon receptor (AhR) responds to endogenous and exogenous ligands as a cytosolic receptor, transcription factor, and E3 ubiquitin ligase. Several studies support an anti-inflammatory effect of AhR activation. However,...
8.
Edwards M, Garcia Mora J, Fowler K, Vezza C, Robertson J, Daniel G, et al.
Vet Comp Oncol
. 2024 Feb;
22(2):174-185.
PMID: 38332673
Meningiomas are the most common feline primary brain tumours, and calvarial hyperostosis (CH) is frequently documented in association with this neoplastic entity. The clinical significance of and mechanisms driving the...
9.
Almond M, Farne H, Jackson M, Jha A, Katsoulis O, Pitts O, et al.
Nat Commun
. 2023 Oct;
14(1):6607.
PMID: 37857661
Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms underlying susceptibility are poorly understood. Here, we identify that obese individuals have deficient pulmonary antiviral immune responses...
10.
Curren B, Ahmed T, Howard D, Ullah M, Sebina I, Rashid R, et al.
Mucosal Immunol
. 2023 Jul;
16(5):671-684.
PMID: 37506849
Rhinovirus-induced neutrophil extracellular traps (NETs) contribute to acute asthma exacerbations; however, the molecular factors that trigger NETosis in this context remain ill-defined. Here, we sought to implicate a role for...