Nathan E Price
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Explore the profile of Nathan E Price including associated specialties, affiliations and a list of published articles.
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22
Citations
417
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Recent Articles
1.
Price N, Gates K
Chem Res Toxicol
. 2024 Jan;
37(2):199-207.
PMID: 38198604
Recent studies have defined a novel pathway for the repair of interstrand cross-links derived from the reaction of an adenine residue with an apurinic/apyrimidinic (AP) site on the opposing strand...
2.
Amin S, Islam T, Price N, Wallace A, Guo X, Gomina A, et al.
ACS Omega
. 2022 Oct;
7(41):36888-36901.
PMID: 36278095
The experiments described here examined the effects of reaction conditions, various additives, and local sequence on the formation and stability interstrand cross-links (ICLs) derived from the reaction of an apurinic/apyrimidinic...
3.
Gamboa Varela J, Pierce L, Guo X, Price N, Johnson K, Yang Z, et al.
Chem Res Toxicol
. 2021 Mar;
34(4):1124-1132.
PMID: 33784065
The formation of interstrand cross-links in duplex DNA is important in biology, medicine, and biotechnology. Interstrand cross-links arising from the reaction of the aldehyde residue of an abasic (apurinic or...
4.
Wu J, Yuan J, Price N, Wang Y
J Biol Chem
. 2020 May;
295(26):8775-8783.
PMID: 32381504
Alkyl phosphotriester (alkyl-PTE) lesions are frequently induced in DNA and are resistant to repair. Here, we synthesized and characterized methyl (Me)- and -butyl (Bu)-PTEs in two diastereomeric configurations ( and...
5.
Tam L, Price N, Wang Y
Chem Res Toxicol
. 2020 Jan;
33(3):709-726.
PMID: 31986875
Exposure to arsenic in contaminated drinking water is an emerging public health problem that impacts more than 200 million people worldwide. Accumulating lines of evidence from epidemiological studies revealed that...
6.
Wu J, Du H, Li L, Price N, Liu X, Wang Y
ACS Chem Biol
. 2019 Jul;
14(8):1708-1716.
PMID: 31347832
Endogenous metabolites and exogenous chemicals can induce covalent modifications on DNA, producing DNA lesions. The of guanine was shown to be a common alkylation site in DNA; however, not much...
7.
Nejad M, Price N, Haldar T, Lewis C, Wang Y, Gates K
ACS Chem Biol
. 2019 Jul;
14(7):1481-1489.
PMID: 31259519
Efficient methods for the site-specific installation of structurally defined interstrand cross-links in duplex DNA may be useful in a wide variety of fields. The work described here developed a high-yield...
8.
Nejad M, Guo X, Housh K, Nel C, Yang Z, Price N, et al.
Methods Mol Biol
. 2019 Apr;
1973:163-175.
PMID: 31016701
Methods for the preparation of DNA duplexes containing interstrand covalent cross-links may facilitate research in the fields of biochemistry, molecular biology, nanotechnology, and materials science. Here we report methods for...
9.
Guo S, Leng J, Tan Y, Price N, Wang Y
Chem Res Toxicol
. 2019 Feb;
32(4):708-717.
PMID: 30714728
Quantitative measurement of DNA adducts in carcinogen-exposed cells provides the information about the frequency of formation and the rate of removal of DNA lesions in vivo, which yields insights into...
10.
Yang Z, Price N, Johnson K, Wang Y, Gates K
Nucleic Acids Res
. 2017 May;
45(11):6275-6283.
PMID: 28531327
Interstrand cross-links are exceptionally bioactive DNA lesions. Endogenous generation of interstrand cross-links in genomic DNA may contribute to aging, neurodegeneration, and cancer. Abasic (Ap) sites are common lesions in genomic...