Nathan E Lewis
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Explore the profile of Nathan E Lewis including associated specialties, affiliations and a list of published articles.
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181
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8108
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Recent Articles
1.
Martino C, Kellman B, Sandoval D, Clausen T, Cooper R, Benjdia A, et al.
mBio
. 2025 Feb;
:e0401524.
PMID: 39998226
The gastrointestinal (GI) tract is a site of replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and GI symptoms are often reported by patients. SARS-CoV-2 cell entry depends upon...
2.
Gomez Toledo A, Chowdhury S, Hjortswang E, Sorrentino J, Lewis N, Blackberg A, et al.
Nat Commun
. 2025 Feb;
16(1):1942.
PMID: 39994218
This study showcases an integrative mass spectrometry-based strategy combining systems antigenomics and systems serology to characterize human antibodies in clinical samples. This strategy involves using antibodies circulating in plasma to...
3.
Hefzi H, Martinez-Monge I, Marin de Mas I, Cowie N, Gomez Toledo A, Noh S, et al.
Nat Metab
. 2025 Jan;
7(1):212-227.
PMID: 39809975
The Warburg effect, which describes the fermentation of glucose to lactate even in the presence of oxygen, is ubiquitous in proliferative mammalian cells, including cancer cells, but poses challenges for...
4.
Tsai C, Hajam I, Caldera J, Chiang A, Gonzalez C, Du X, et al.
J Clin Invest
. 2024 Dec;
134(24).
PMID: 39680460
The pathobiont Staphylococcus aureus (Sa) induces nonprotective antibody imprints that underlie ineffective staphylococcal vaccination. However, the mechanism by which Sa modifies antibody activity is not clear. Herein, we demonstrate that...
5.
Pribic T, Das J, derek L, Belsky D, Orenduff M, Huffman K, et al.
medRxiv
. 2024 Dec;
PMID: 39677441
Background/objective: In a subset of participants from the CALERIE Phase 2 study we evaluated the effects of 2y of ~25% Calorie Restriction (CR) diet on IgG N-glycosylation (GlycAge), plasma and...
6.
Jumabay M, Abud E, Okamoto K, Dutta P, Chiang A, Li H, et al.
J Allergy Clin Immunol
. 2024 Dec;
PMID: 39617290
Background: Pathologic tissue remodeling with scarring and tissue rigidity has been demonstrated in inflammatory, autoimmune, and allergic diseases. Eosinophilic esophagitis (EoE) is an allergic disease that is diagnosed and managed...
7.
Kavoni H, Savizi I, Lewis N, Shojaosadati S
Biotechnol Adv
. 2024 Nov;
78:108480.
PMID: 39571767
The production of monoclonal antibodies (mAbs) using Chinese Hamster Ovary (CHO) cells has revolutionized the treatment of numerous diseases, solidifying their position as a cornerstone of the biopharmaceutical industry. However,...
8.
Baek M, Kim C, Kim S, Karottki K, Hefzi H, Grav L, et al.
Metab Eng
. 2024 Nov;
87:11-20.
PMID: 39566816
Chinese hamster ovary (CHO) cells, which are widely used for therapeutic protein production, have been genetically manipulated to enhance productivity. Nearly half of the genes in CHO cells are silenced,...
9.
Scapin G, Cagdas E, Grav L, Lewis N, Goletz S, Hafkenscheid L
Biotechnol Adv
. 2024 Oct;
77:108467.
PMID: 39447666
Cytokines are important regulators of immune responses, making them attractive targets for autoimmune diseases and cancer therapeutics. Yet, the significance of cytokine glycosylation remains underestimated. Many cytokines carry N- and...
10.
Zahiri J, Mirzaie M, Duan K, Xiao Y, Aamodt C, Yang X, et al.
medRxiv
. 2024 Oct;
PMID: 39399028
Some toddlers with autism spectrum disorder (ASD) have mild social symptoms and developmental improvement in skills, but for others, symptoms and abilities are moderately or even severely affected. Those with...