Nathan C Kuhn
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Explore the profile of Nathan C Kuhn including associated specialties, affiliations and a list of published articles.
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13
Citations
222
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Recent Articles
1.
Choza J, Virani M, Kuhn N, Adams M, Kochmanski J, Bernstein A
bioRxiv
. 2025 Feb;
PMID: 39975085
Epigenetic mechanisms are mediators of interactions between aging, genetics, and environmental factors in sporadic Parkinson's disease (PD). Multiple studies have explored the DNA modifications in PD, but few focus on...
2.
Choza J, Virani M, Kuhn N, Adams M, Kochmanski J, Bernstein A
Res Sq
. 2024 Jul;
PMID: 39070644
Background: The majority of Parkinson's disease (PD) cases are due to a complex interaction between aging, genetics, and environmental factors; epigenetic mechanisms are thought to act as important mediators of...
3.
Kochmanski J, Virani M, Kuhn N, Boyd S, Becker K, Adams M, et al.
Toxicol Sci
. 2024 Jul;
201(2):263-281.
PMID: 38995845
Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is associated with an increased risk of Parkinson's disease (PD). Animal studies support a link between developmental dieldrin exposure and...
4.
Kochmanski J, Virani M, Kuhn N, Boyd S, Becker K, Adams M, et al.
bioRxiv
. 2024 May;
PMID: 38746441
Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson's disease (PD). Animal studies support a link between developmental dieldrin exposure and increased...
5.
Patterson J, Kochmanski J, Stoll A, Kubik M, Kemp C, Duffy M, et al.
NPJ Parkinsons Dis
. 2024 Jan;
10(1):7.
PMID: 38172128
Examination of early phases of synucleinopathy when inclusions are present, but long before neurodegeneration occurs, is critical to both understanding disease progression and the development of disease modifying therapies. The...
6.
Boyd S, Kuhn N, Patterson J, Stoll A, Zimmerman S, Kolanowski M, et al.
Toxicol Sci
. 2023 Aug;
196(1):99-111.
PMID: 37607008
Parkinson's disease (PD) is the fastest-growing neurological disease worldwide, with increases outpacing aging and occurring most rapidly in recently industrialized areas, suggesting a role of environmental factors. Epidemiological, post-mortem, and...
7.
Kochmanski J, Kuhn N, Bernstein A
NPJ Parkinsons Dis
. 2022 Sep;
8(1):120.
PMID: 36151217
Evidence for epigenetic regulation playing a role in Parkinson's disease (PD) is growing, particularly for DNA methylation. Approximately 90% of PD cases are due to a complex interaction between age,...
8.
Gordevicius J, Li P, Marshall L, Killinger B, Lang S, Ensink E, et al.
Nat Commun
. 2021 Aug;
12(1):5134.
PMID: 34446734
The gastrointestinal tract may be a site of origin for α-synuclein pathology in idiopathic Parkinson's disease (PD). Disruption of the autophagy-lysosome pathway (ALP) may contribute to α-synuclein aggregation. Here we...
9.
Gezer A, Kochmanski J, VanOeveren S, Cole-Strauss A, Kemp C, Patterson J, et al.
Neurobiol Dis
. 2020 May;
141:104947.
PMID: 32422283
Human and animal studies have shown that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson's disease (PD). Previous work showed that developmental dieldrin exposure increased...
10.
Benskey M, Sandoval I, Miller K, Sellnow R, Gezer A, Kuhn N, et al.
Methods Mol Biol
. 2019 Feb;
1937:3-26.
PMID: 30706387
Today any researcher with the desire can easily purchase a viral vector. However, despite the availability of viral vectors themselves, the requisite knowledge that is absolutely essential to conducting a...