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Alison I Bernstein

Explore the profile of Alison I Bernstein including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 532
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Recent Articles
1.
Choza J, Virani M, Kuhn N, Adams M, Kochmanski J, Bernstein A
bioRxiv . 2025 Feb; PMID: 39975085
Epigenetic mechanisms are mediators of interactions between aging, genetics, and environmental factors in sporadic Parkinson's disease (PD). Multiple studies have explored the DNA modifications in PD, but few focus on...
2.
Choza J, Virani M, Kuhn N, Adams M, Kochmanski J, Bernstein A
Res Sq . 2024 Jul; PMID: 39070644
Background: The majority of Parkinson's disease (PD) cases are due to a complex interaction between aging, genetics, and environmental factors; epigenetic mechanisms are thought to act as important mediators of...
3.
Kochmanski J, Virani M, Kuhn N, Boyd S, Becker K, Adams M, et al.
Toxicol Sci . 2024 Jul; 201(2):263-281. PMID: 38995845
Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is associated with an increased risk of Parkinson's disease (PD). Animal studies support a link between developmental dieldrin exposure and...
4.
Kochmanski J, Virani M, Kuhn N, Boyd S, Becker K, Adams M, et al.
bioRxiv . 2024 May; PMID: 38746441
Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson's disease (PD). Animal studies support a link between developmental dieldrin exposure and increased...
5.
Gionco J, Bernstein A
J Parkinsons Dis . 2024 Apr; 14(4):643-656. PMID: 38578904
Environmental risk factors and gene-environment interactions play a critical role in Parkinson's disease (PD). However, the relatively large contribution of environmental risk factors in the overwhelming majority of PD cases...
6.
Patterson J, Kochmanski J, Stoll A, Kubik M, Kemp C, Duffy M, et al.
NPJ Parkinsons Dis . 2024 Jan; 10(1):7. PMID: 38172128
Examination of early phases of synucleinopathy when inclusions are present, but long before neurodegeneration occurs, is critical to both understanding disease progression and the development of disease modifying therapies. The...
7.
Boyd S, Kuhn N, Patterson J, Stoll A, Zimmerman S, Kolanowski M, et al.
Toxicol Sci . 2023 Aug; 196(1):99-111. PMID: 37607008
Parkinson's disease (PD) is the fastest-growing neurological disease worldwide, with increases outpacing aging and occurring most rapidly in recently industrialized areas, suggesting a role of environmental factors. Epidemiological, post-mortem, and...
8.
Kochmanski J, Kuhn N, Bernstein A
NPJ Parkinsons Dis . 2022 Sep; 8(1):120. PMID: 36151217
Evidence for epigenetic regulation playing a role in Parkinson's disease (PD) is growing, particularly for DNA methylation. Approximately 90% of PD cases are due to a complex interaction between age,...
9.
Gezer A, Kochmanski J, VanOeveren S, Cole-Strauss A, Kemp C, Patterson J, et al.
Neurobiol Dis . 2020 May; 141:104947. PMID: 32422283
Human and animal studies have shown that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson's disease (PD). Previous work showed that developmental dieldrin exposure increased...
10.
Kochmanski J, Bernstein A
Curr Environ Health Rep . 2020 Feb; 7(2):109-120. PMID: 32020534
Purpose Of Review: The aims of this review are to evaluate the methods used to measure 5-hydroxymethylcytosine (5-hmC), and then summarize the available data investigating the impact of environmental factors...