When Monoclonal Gammopathy-associated Chronic Neutrophilic Leukemia is a Reactive Process Distinct from a Clonal Myeloproliferative Neoplasm: Lessons from Mistakes

Overview

Journal EJHaem

Specialty Hematology

Date 2023 Aug 21

PMID 37601857

Authors

Christophe Willekens

Claude Chahine

Matteo Dragani

Sabine Khalife-Hachem

Camille Bigenwald

Julien Rossignol

Cristina Castilla-Llorente

Alina Danu

Jean-Marie Michot

Veronique Saada

Sophie Cotteret

Christophe Marzac

Aline Renneville

Isabelle Plo

Sophie Broutin

Nelly Bosselut

Bruno Cassinat

Julien Lazarovici

Nathalie Droin

Stephane de Botton

Affiliations

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When monoclonal gammopathy-associated chronic neutrophilic leukemia is a reactive process distinct from a clonal myeloproliferative neoplasm: Lessons from mistakes.

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References

Khoury J, Solary E, Abla O, Akkari Y, Alaggio R, Apperley J . The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia. 2022; 36(7):1703-1719. PMC: 9252913. DOI: 10.1038/s41375-022-01613-1. View

Bain B, Ahmad S . Chronic neutrophilic leukaemia and plasma cell-related neutrophilic leukaemoid reactions. Br J Haematol. 2015; 171(3):400-10. DOI: 10.1111/bjh.13600. View

Nagai M, Oda S, Iwamoto M, Marumoto K, Fujita M, Takahara J . Granulocyte-colony stimulating factor concentrations in a patient with plasma cell dyscrasia and clinical features of chronic neutrophilic leukaemia. J Clin Pathol. 1996; 49(10):858-60. PMC: 500786. DOI: 10.1136/jcp.49.10.858. View

Taiwo E, Wang H, Lewis R . Treatment of coexisting chronic neutrophilic leukemia and light chain multiple myeloma with hydroxyurea, bortezomib, and dexamethasone. Case Rep Hematol. 2014; 2014:869395. PMC: 4124778. DOI: 10.1155/2014/869395. View

Vermeersch G, Delforge M, Havelange V, Graux C, Michaux L, Devos T . Case report: Chronic neutrophilic leukemia associated with monoclonal gammopathies. A case series and review of genetic characteristics and practical management. Front Oncol. 2022; 12:1014671. PMC: 9768602. DOI: 10.3389/fonc.2022.1014671. View

Maxson J, Luty S, MacManiman J, Paik J, Gotlib J, Greenberg P . The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I. Clin Cancer Res. 2015; 22(3):757-64. PMC: 4738027. DOI: 10.1158/1078-0432.CCR-14-3100. View

Szuber N, Elliott M, Tefferi A . Chronic neutrophilic leukemia: 2022 update on diagnosis, genomic landscape, prognosis, and management. Am J Hematol. 2022; 97(4):491-505. DOI: 10.1002/ajh.26481. View

Willekens C, Chahine C, Dragani M, Khalife-Hachem S, Bigenwald C, Rossignol J . When monoclonal gammopathy-associated chronic neutrophilic leukemia is a reactive process distinct from a clonal myeloproliferative neoplasm: Lessons from mistakes. EJHaem. 2023; 4(3):823-826. PMC: 10435719. DOI: 10.1002/jha2.713. View

Plo I, Zhang Y, Le Couedic J, Nakatake M, Boulet J, Itaya M . An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia. J Exp Med. 2009; 206(8):1701-7. PMC: 2722170. DOI: 10.1084/jem.20090693. View

10.

Bilbao-Sieyro C, Santana G, Torres-Minana L, Rodriguez-Medina C, Saez M, Perera M . Colony-stimulating factor-3 receptor, watch out for polymorphisms. Leukemia. 2015; 29(6):1445-6. DOI: 10.1038/leu.2015.25. View

11.

Maxson J, Gotlib J, Pollyea D, Fleischman A, Agarwal A, Eide C . Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML. N Engl J Med. 2013; 368(19):1781-90. PMC: 3730275. DOI: 10.1056/NEJMoa1214514. View

12.

Williams L, Doucette K, Karp J, Lai C . Genetics of donor cell leukemia in acute myelogenous leukemia and myelodysplastic syndrome. Bone Marrow Transplant. 2021; 56(7):1535-1549. DOI: 10.1038/s41409-021-01214-z. View

13.

Stevens B, Maxson J, Tyner J, Smith C, Gutman J, Robinson W . Clonality of neutrophilia associated with plasma cell neoplasms: report of a SETBP1 mutation and analysis of a single institution series. Leuk Lymphoma. 2015; 57(4):927-34. PMC: 4794392. DOI: 10.3109/10428194.2015.1094697. View