Natee Jearawiriyapaisarn
Overview
Explore the profile of Natee Jearawiriyapaisarn including associated specialties, affiliations and a list of published articles.
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27
Citations
449
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Recent Articles
1.
Janpipatkul K, Sutjarit N, Tangprasittipap A, Chaiamarit T, Innachai P, Suksen K, et al.
Orphanet J Rare Dis
. 2024 Oct;
19(1):363.
PMID: 39358794
Background: Gaucher disease (GD) is one of the most common types of lysosomal storage diseases (LSDs) caused by pathogenic variants of lysosomal β-glucocerebrosidase gene (GBA1), resulting in the impairment of...
2.
Pongpaksupasin P, Tong-Ngam P, Jearawiriyapaisarn N, Paiboonsukwong K, Sangkitporn S, Trinavarat A, et al.
Stem Cell Res
. 2024 May;
78:103448.
PMID: 38810502
Mutations in the eyes shut homolog (EYS) gene are one of the common causes of autosomal recessive retinitis pigmentosa (RP). The lack of suitable animal models hampers progress understanding of...
3.
Penglong T, Saensuwanna A, Jantapaso H, Phuwakanjana P, Jearawiriyapaisarn N, Paiboonsukwong K, et al.
PLoS One
. 2024 Apr;
19(4):e0300958.
PMID: 38625890
Oxidative damage to erythroid cells plays a key role in the pathogenesis of thalassemia. The oxidative stress in thalassemia is potentiated by heme, nonheme iron, and free iron produced by...
4.
Singpant P, Tubsuwan A, Sakdee S, Ketterman A, Jearawiriyapaisarn N, Kurita R, et al.
Protein Expr Purif
. 2023 Jun;
210:106313.
PMID: 37276914
Many therapeutic proteins are expressed in Escherichia coli bacteria for the low cost and high yield obtained. However, these gram-negative bacteria also generate undesirable endotoxin byproducts such as lipopolysaccharides (LPS)....
5.
Chumchuen S, Sripichai O, Jearawiriyapaisarn N, Fucharoen S, Peerapittayamongkol C
PLoS One
. 2023 Mar;
18(3):e0281059.
PMID: 36888630
Imbalanced globin chain output contributes to thalassemia pathophysiology. Hence, induction of fetal hemoglobin in β-thalassemia and other β-hemoglobinopathies are of continuing interest for therapeutic approaches. Genome-wide association studies have identified...
6.
Pongpaksupasin P, Wongkummool W, Tong-Ngam P, Jearawiriyapaisarn N, Paiboonsukwong K, Sangkitporn S, et al.
Stem Cell Res
. 2022 Nov;
65:102964.
PMID: 36395688
Choroideremia (CHM) is a monogenic, X-linked inherited retinal disease caused by mutations in the CHM gene. CHM patients develop progressive loss of vision due to degeneration of cell layers in...
7.
Yu L, Myers G, Schneider E, Wang Y, Mathews R, Lim K, et al.
Blood Adv
. 2022 Mar;
6(11):3280-3285.
PMID: 35240686
Human γ-globin is predominantly expressed in fetal liver erythroid cells during gestation from 2 nearly identical genes, HBG1 and HBG2, that are both perinatally silenced. Reactivation of these fetal genes...
8.
Kaewsakulthong W, Pongpaksupasin P, Nualkaew T, Hongeng S, Fucharoen S, Jearawiriyapaisarn N, et al.
Hematol Rep
. 2022 Jan;
13(4):9215.
PMID: 35003571
Induction of fetal hemoglobin (HbF) ameliorates the clinical severity of β-thalassemias. Histone methyltransferase LSD1 enzyme removes methyl groups from the activating chromatin mark histone 3 lysine 4 at silenced genes,...
9.
Khamphikham P, Jearawiriyapaisarn N, Tangprasittipap A, Hongeng S
Exp Ther Med
. 2021 Sep;
22(4):1105.
PMID: 34504559
The Krüppel-like factor (KLF) family dominates highly conserved three zinc finger DNA binding domains at the C-terminus and variable transactivation domains at the N-terminus. Humans possess 18 genes that are...
10.
Yu L, Myers G, Ku C, Schneider E, Wang Y, Singh S, et al.
Blood
. 2021 Jul;
138(18):1691-1704.
PMID: 34324630
Histone H3 lysine 4 methylation (H3K4Me) is most often associated with chromatin activation, and removing H3K4 methyl groups has been shown to be coincident with gene repression. H3K4Me demethylase KDM1a/LSD1...