Natascha Van Pelt
Overview
Explore the profile of Natascha Van Pelt including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
35
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Recent Articles
1.
Carnamucio F, Foti C, Micale N, Van Pelt N, Matheeussen A, Caljon G, et al.
ACS Omega
. 2024 Jul;
9(26):29000-29008.
PMID: 38973913
Metronidazole (2-methyl-5-nitro-1-imidazole-1-ethanol, MNZ) is a well-known and widely used drug for its excellent activity against various anaerobic bacteria and protozoa. The purpose of this study is to elucidate the ability...
2.
Bozdag M, Mertens F, Matheeussen A, Van Pelt N, Foubert K, Hermans N, et al.
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38731916
Herein, we report a series of 1,3-diarylpyrazoles that are analogues of compound /HIT 8. We previously identified this molecule as a 'hit' during a high-throughput screening campaign for autophagy inducers....
3.
Hartman C, Dube P, Legoabe L, Van Pelt N, Matheeussen A, Caljon G, et al.
Arch Pharm (Weinheim)
. 2024 Feb;
357(6):e2300319.
PMID: 38396284
Several quinoline derivatives incorporating arylnitro and aminochalcone moieties were synthesized and evaluated in vitro against a broad panel of trypanosomatid protozoan parasites responsible for sleeping sickness (Trypanosoma brucei rhodesiense), nagana...
4.
Braillard S, Keenan M, Breese K, Heppell J, Abbott M, Islam R, et al.
Sci Transl Med
. 2023 Dec;
15(726):eadh9902.
PMID: 38091406
New drugs for visceral leishmaniasis that are safe, low cost, and adapted to the field are urgently required. Despite concerted efforts over the last several years, the number of new...
5.
de Oliveira Rezende Junior C, Martinez P, Ferreira R, Koovits P, Miranda Soares B, Ferreira L, et al.
Eur J Med Chem
. 2022 Dec;
246:114925.
PMID: 36459758
Chagas disease is a neglected tropical disease caused by Trypanosoma cruzi. Because current treatments present several limitations, including long duration, variable efficacy and serious side effects, there is an urgent...
6.
Peeters L, Foubert K, Balde M, Tuenter E, Matheeussen A, Van Pelt N, et al.
Phytochemistry
. 2021 Nov;
194:113029.
PMID: 34844038
Nauclea pobeguinii is traditionally used for treatment of malaria. Previous studies on the plant extract and strictosamide, the putative active constituent, showed a profound in vivo activity of the extract...
7.
Szelid Z, Sinnaeve P, Vermeersch P, Gillijns H, Pellens M, Laurysens V, et al.
Hum Gene Ther
. 2003 Jan;
13(18):2185-95.
PMID: 12542849
The utility of adenoviral vectors, currently used in cardiovascular gene transfer protocols, is limited by the brevity of transgene expression and by antiadenoviral immune responses. The effect of preexisting antiadenoviral...
8.
Sinnaeve P, Chiche J, Gillijns H, Van Pelt N, Wirthlin D, Van de Werf F, et al.
Circulation
. 2002 Jun;
105(24):2911-6.
PMID: 12070122
Background: Neointima formation after arterial injury is associated with reduced vascular cyclic guanosine monophosphate (cGMP) and cGMP-dependent protein kinase (PKG), a major cGMP effector in vascular smooth muscle. We tested...