Nasrollah Rezaei-Ghaleh
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Explore the profile of Nasrollah Rezaei-Ghaleh including associated specialties, affiliations and a list of published articles.
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55
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1122
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Recent Articles
1.
Chakrabarti K, Bakhtiari D, Rezaei-Ghaleh N
NPJ Syst Biol Appl
. 2024 Jul;
10(1):80.
PMID: 39080352
A complex interplay between various processes underlies the neuropathology of Alzheimer's disease (AD) and its progressive course. Several lines of evidence point to the coupling between Aβ aggregation and neuroinflammation...
2.
Nimerovsky E, Sieme D, Rezaei-Ghaleh N
Methods
. 2024 May;
228:55-64.
PMID: 38782295
Metal ions, including biologically prevalent sodium ions, can modulate electrostatic interactions frequently involved in the stability of condensed compartments in cells. Quantitative characterization of heterogeneous ion dynamics inside biomolecular condensates...
3.
Sicoli G, Sieme D, Overkamp K, Khalil M, Backer R, Griesinger C, et al.
Nat Commun
. 2024 Feb;
15(1):1610.
PMID: 38383529
Liquid-liquid phase separation is the key process underlying formation of membrane-less compartments in cells. A highly dynamic cellular body with rapid component exchange is Cajal body (CB), which supports the...
4.
Sieme D, Engelke M, Rezaei-Ghaleh N, Becker S, Wienands J, Griesinger C
J Am Chem Soc
. 2023 Dec;
146(1):399-409.
PMID: 38111344
Signal transduction by the ligated B cell antigen receptor (BCR) depends on the preorganization of its intracellular components, such as the effector proteins SLP65 and CIN85 within phase-separated condensates. These...
5.
Sieme D, Rezaei-Ghaleh N
Phys Chem Chem Phys
. 2023 Dec;
26(1):105-115.
PMID: 38054803
Liquid water is essential for life as we know it and the coupling between water and biomolecular dynamics is crucial for life processes. Jupiter's moon Europa is a good candidate...
6.
Becker S, Giller K, Sieme D, Rezaei-Ghaleh N
Phys Chem Chem Phys
. 2023 May;
25(22):15099-15103.
PMID: 37249476
Little is known about how maturation of Alzheimer's disease-related amyloid β (Aβ) fibrils alters their stability and potentially influences their spreading in the brain. Using high-pressure NMR, we show that...
7.
Rezaei-Ghaleh N, Amininasab M, Giller K, Becker S
J Phys Chem Lett
. 2023 Feb;
14(6):1427-1435.
PMID: 36734539
Amyloid-beta (Aβ) deposition as senile plaques is a pathological hallmark of Alzheimer's disease (AD). AD is characterized by a large level of heterogeneity in amyloid pathology, whose molecular origin is...
8.
Abyzov A, Mandelkow E, Zweckstetter M, Rezaei-Ghaleh N
Chemistry
. 2022 Dec;
29(17):e202203493.
PMID: 36579699
Reorientational dynamics of intrinsically disordered proteins (IDPs) contain multiple motions often clustered around three motional modes: ultrafast librational motions of amide groups, fast local backbone conformational fluctuations and slow chain...
9.
Sieme D, Griesinger C, Rezaei-Ghaleh N
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361973
Heparins and heparan sulfate polysaccharides are negatively charged glycosaminoglycans and play important roles in cell-to-matrix and cell-to-cell signaling processes. Metal ion binding to heparins alters the conformation of heparins and...
10.
Rafiei Y, Salmani B, Mirzaei-Behbahani B, Taleb M, Meratan A, Ramezani M, et al.
ACS Chem Neurosci
. 2022 Oct;
13(22):3168-3179.
PMID: 36314062
Natural compounds with anti-aggregation capacity are increasingly recognized as viable candidates against neurodegenerative diseases. Recently, the polyphenolic fraction of propolis (PFP), a complex bee product, has been shown to inhibit...