Naohito Nozaki
Overview
Explore the profile of Naohito Nozaki including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
2690
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Recent Articles
1.
Hayashi-Takanaka Y, Kina Y, Nakamura F, Becking L, Nakao Y, Nagase T, et al.
J Cell Sci
. 2020 Jun;
133(14).
PMID: 32576661
Post-translational modifications on histones can be stable epigenetic marks or transient signals that can occur in response to internal and external stimuli. Levels of histone modifications fluctuate during the cell...
2.
Nakanishi A, Hatano N, Fujiwara Y, Shari A, Takabatake S, Akano H, et al.
J Biol Chem
. 2017 Oct;
292(48):19804-19813.
PMID: 28974582
The Ca/calmodulin-dependent protein kinase kinase β (CaMKKβ)/5'-AMP-activated protein kinase (AMPK) phosphorylation cascade affects various Ca-dependent metabolic pathways and cancer growth. Unlike recombinant CaMKKβ that exhibits higher basal activity (autonomous activity),...
3.
Isobe S, Nagao K, Nozaki N, Kimura H, Obuse C
Cell Rep
. 2017 Jul;
20(2):297-307.
PMID: 28700933
DNA double-strand breaks (DSBs) are repaired by either the homology-directed repair (HDR) or the non-homologous end-joining (NHEJ) pathway. RIF1 (RAP1-interacting factor homolog) was recently shown to stimulate NHEJ through an...
4.
Kaimori J, Maehara K, Hayashi-Takanaka Y, Harada A, Fukuda M, Yamamoto S, et al.
Sci Rep
. 2016 Apr;
6:24318.
PMID: 27064113
Histone acetylation is generally associated with gene activation and chromatin decondensation. Recent mass spectrometry analysis has revealed that histone H4 lysine 20, a major methylation site, can also be acetylated....
5.
Hayashi-Takanaka Y, Maehara K, Harada A, Umehara T, Yokoyama S, Obuse C, et al.
Chromosome Res
. 2015 Sep;
23(4):753-66.
PMID: 26343042
Post-translational histone modifications play a critical role in genome functions such as epigenetic gene regulation and genome maintenance. The tail of the histone H4 N-terminus contains several amino acids that...
6.
Stasevich T, Hayashi-Takanaka Y, Sato Y, Maehara K, Ohkawa Y, Sakata-Sogawa K, et al.
Nature
. 2014 Sep;
516(7530):272-5.
PMID: 25252976
In eukaryotic cells, post-translational histone modifications have an important role in gene regulation. Starting with early work on histone acetylation, a variety of residue-specific modifications have now been linked to...
7.
Hayashi-Takanaka Y, Stasevich T, Kurumizaka H, Nozaki N, Kimura H
PLoS One
. 2014 Sep;
9(9):e106271.
PMID: 25184362
To optimize live cell fluorescence imaging, the choice of fluorescent substrate is a critical factor. Although genetically encoded fluorescent proteins have been used widely, chemical fluorescent dyes are still useful...
8.
Stasevich T, Sato Y, Nozaki N, Kimura H
Methods
. 2014 Aug;
70(2-3):77-88.
PMID: 25131722
Post-translational histone modifications are highly correlated with transcriptional activity, but the relative timing of these marks and their dynamic interplay during gene regulation remains controversial. To shed light on this...
9.
Maejima T, Inoue T, Kanki Y, Kohro T, Li G, Ohta Y, et al.
PLoS One
. 2014 May;
9(5):e96005.
PMID: 24797675
Statins exert atheroprotective effects through the induction of specific transcriptional factors in multiple organs. In endothelial cells, statin-dependent atheroprotective gene up-regulation is mediated by Kruppel-like factor (KLF) family transcription factors....
10.
Kaiser F, Ansari M, Braunholz D, Gil-Rodriguez M, Decroos C, Wilde J, et al.
Hum Mol Genet
. 2014 Jan;
23(11):2888-900.
PMID: 24403048
Cornelia de Lange syndrome (CdLS) is a multisystem genetic disorder with distinct facies, growth failure, intellectual disability, distal limb anomalies, gastrointestinal and neurological disease. Mutations in NIPBL, encoding a cohesin...